SNAP25-AS1

gene

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Summary

SNAP25-AS1 (SNAP25 antisense RNA 1, HGNC:44312) is a long non-coding RNA gene on chromosome 20p12.2.

Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting.

Source: NCBI Gene 100131208 — RefSeq curated summary.

At a glance

Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44312
Approved symbol	SNAP25-AS1
Name	SNAP25 antisense RNA 1
Location	20p12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227906
Ensembl biotype	lncRNA
Entrez	100131208
RNAcentral	URS000075B5B7 — lncRNA, 2959 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 32 lncRNA

ENST00000421143, ENST00000426491, ENST00000438646, ENST00000451151, ENST00000453544, ENST00000603245, ENST00000603542, ENST00000605592, ENST00000655307, ENST00000655841, ENST00000656496, ENST00000658443, ENST00000658520, ENST00000660550, ENST00000661134, ENST00000661614, ENST00000662559, ENST00000663466, ENST00000664172, ENST00000666905, ENST00000667042, ENST00000670580, ENST00000671416, ENST00000671453, ENST00000692436, ENST00000701361, ENST00000807507, ENST00000807508, ENST00000807509, ENST00000807510, ENST00000807511, ENST00000807512

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421143 — 4 exons

Exon	Start	End
ENSE00001681685	10196818	10196937
ENSE00001728322	10104286	10104394
ENSE00004201645	10368715	10368846
ENSE00004201654	10026075	10026648

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 87.91.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4645 / max 38.6454, expressed in 183 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
186405	0.3248	147
186406	0.1193	59
186412	0.0204	8

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	87.91	silver quality
colonic epithelium	UBERON:0000397	79.33	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.47	gold quality
cerebellar hemisphere	UBERON:0002245	75.02	gold quality
cerebellar cortex	UBERON:0002129	74.96	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.97	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.92	gold quality
cerebellum	UBERON:0002037	73.91	gold quality
prefrontal cortex	UBERON:0000451	71.56	gold quality
anterior cingulate cortex	UBERON:0009835	71.19	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.22	gold quality
islet of Langerhans	UBERON:0000006	69.80	gold quality
medial globus pallidus	UBERON:0002477	69.60	gold quality
right frontal lobe	UBERON:0002810	69.19	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.06	gold quality
neocortex	UBERON:0001950	68.99	gold quality
frontal cortex	UBERON:0001870	68.77	gold quality
bone marrow cell	CL:0002092	68.67	silver quality
nucleus accumbens	UBERON:0001882	68.55	gold quality
hypothalamus	UBERON:0001898	68.52	gold quality
pituitary gland	UBERON:0000007	67.94	gold quality
cerebral cortex	UBERON:0000956	67.42	gold quality
brain	UBERON:0000955	67.36	gold quality
primary visual cortex	UBERON:0002436	66.98	gold quality
globus pallidus	UBERON:0001875	66.97	gold quality
amygdala	UBERON:0001876	66.85	gold quality
forebrain	UBERON:0001890	66.74	gold quality
ventricular zone	UBERON:0003053	66.60	gold quality
adenohypophysis	UBERON:0002196	66.26	gold quality
tendon of biceps brachii	UBERON:0008188	66.15	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 3.

Experiment	Marker?	Max mean expression
E-HCAD-25	yes	1301.31
E-HCAD-35	yes	344.03
E-ANND-3	yes	4.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.