SNAR-I

Summary

SNAR-I (small NF90 (ILF3) associated RNA I, HGNC:34330) is a gene on chromosome 3q28.

At a glance

• GWAS associations: 8

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:34330
Approved symbol	SNAR-I
Name	small NF90 (ILF3) associated RNA I
Location	3q28
Locus type	RNA, misc
Status	Approved
Aliases	snaR-3
Entrez	100170222
RNAcentral	URS000075BAB5 — snRNA, 121 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1002032225 (3:190878415 G>A), RS1003033218 (3:190877247 G>A), RS1003233306 (3:190877579 G>A,C), RS1005431666 (3:190877597 C>A,G), RS1006467272 (3:190876098 T>A), RS1008939921 (3:190878091 G>A,T), RS1010877849 (3:190878364 C>G,T), RS1016525670 (3:190877621 A>G), RS1016843519 (3:190877939 T>A,C), RS1022809973 (3:190878364 CTT>C), RS1023389654 (3:190876939 G>A), RS1023580546 (3:190876605 A>G,T), RS1028991537 (3:190877681 G>A), RS1032514188 (3:190876328 A>G), RS1034808585 (3:190878433 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

8 associations (top):

Study	Trait	p-value
GCST001951_1	Alzheimer’s disease biomarkers	5.000000e-09
GCST003488_14	Response to fenofibrate (triglyceride levels)	8.000000e-07
GCST004070_11	Cerebrospinal P-tau181p levels	6.000000e-10
GCST004071_3	Cerebrospinal T-tau levels	3.000000e-11
GCST007147_1	Lateral ventricular volume in normal aging	1.000000e-16
GCST008839_334	Height	6.000000e-17
GCST008839_526	Height	9.000000e-12
GCST011617_4	Cortical surface area	2.000000e-13

EFO canonical traits (4, from GWAS)

EFO ID	Trait name
EFO:0004760	t-tau measurement
EFO:0007681	triglyceride change measurement
EFO:0004763	p-tau measurement
EFO:0008487	lateral ventricle volume measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	increases expression	1
Benzo(a)pyrene	increases methylation	1
Valproic Acid	increases methylation	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.