SNCA-AS1

Summary

SNCA-AS1 (SNCA antisense RNA 1, HGNC:50600) is a long non-coding RNA gene on chromosome 4q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50600
Approved symbol	SNCA-AS1
Name	SNCA antisense RNA 1
Location	4q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247775
Ensembl biotype	lncRNA
Entrez	644248
RNAcentral	URS000075B38D — lncRNA, 821 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000501215, ENST00000513653, ENST00000777108, ENST00000777109, ENST00000777110

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501215 — 2 exons

Exon	Start	End
ENSE00001969053	89838261	89840595
ENSE00001972875	89836424	89836734

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 70.43.

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	70.43	gold quality
bone marrow	UBERON:0002371	61.44	gold quality
ganglionic eminence	UBERON:0004023	58.28	silver quality
monocyte	CL:0000576	56.63	gold quality
tonsil	UBERON:0002372	56.53	silver quality
muscle tissue	UBERON:0002385	52.72	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.34	gold quality
prefrontal cortex	UBERON:0000451	51.88	gold quality
cerebellum	UBERON:0002037	51.77	gold quality
cerebellar cortex	UBERON:0002129	51.77	gold quality
cerebellar hemisphere	UBERON:0002245	51.69	gold quality
blood	UBERON:0000178	51.15	gold quality
primary visual cortex	UBERON:0002436	49.81	gold quality
pituitary gland	UBERON:0000007	49.56	gold quality
gall bladder	UBERON:0002110	49.12	gold quality
kidney	UBERON:0002113	48.97	gold quality
adenohypophysis	UBERON:0002196	48.83	gold quality
smooth muscle tissue	UBERON:0001135	48.65	gold quality
superior frontal gyrus	UBERON:0002661	48.55	gold quality
islet of Langerhans	UBERON:0000006	48.21	silver quality
placenta	UBERON:0001987	48.06	gold quality
granulocyte	CL:0000094	47.55	silver quality
frontal cortex	UBERON:0001870	47.39	gold quality
endometrium	UBERON:0001295	46.53	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	46.14	silver quality
brain	UBERON:0000955	46.13	gold quality
heart left ventricle	UBERON:0002084	45.96	silver quality
Brodmann (1909) area 9	UBERON:0013540	45.93	gold quality
ectocervix	UBERON:0012249	45.89	gold quality
adrenal tissue	UBERON:0018303	45.34	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.