SNHG21

Summary

SNHG21 (small nucleolar RNA host gene 21, HGNC:50284) is a long non-coding RNA gene on chromosome 15q25.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50284
Approved symbol	SNHG21
Name	small nucleolar RNA host gene 21
Location	15q25.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	SCARNA15HG, FSD2-AS1, RP11-752G15.6
Ensembl gene	ENSG00000250988
Ensembl biotype	lncRNA
Entrez	100505616
RNAcentral	URS000075A784 — lncRNA, 810 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 17 lncRNA, 1 retained_intron

ENST00000544685, ENST00000558174, ENST00000558687, ENST00000559366, ENST00000561107, ENST00000607520, ENST00000715383, ENST00000834480, ENST00000834481, ENST00000834482, ENST00000834483, ENST00000834484, ENST00000834485, ENST00000834486, ENST00000834487, ENST00000834488, ENST00000834489, ENST00000834490

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000544685 — 2 exons

Exon	Start	End
ENSE00004251967	82750564	82750848
ENSE00004251968	82754629	82757206

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 89.83.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.7110 / max 57.4145, expressed in 1541 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
148102	4.7110	1541

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.83	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.70	gold quality
gastrocnemius	UBERON:0001388	84.34	gold quality
cerebellar hemisphere	UBERON:0002245	84.17	gold quality
right hemisphere of cerebellum	UBERON:0014890	84.17	gold quality
cerebellum	UBERON:0002037	84.09	gold quality
cerebellar cortex	UBERON:0002129	84.07	gold quality
nucleus accumbens	UBERON:0001882	83.71	gold quality
muscle of leg	UBERON:0001383	83.55	gold quality
putamen	UBERON:0001874	83.34	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	82.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	82.71	gold quality
anterior cingulate cortex	UBERON:0009835	82.66	gold quality
caudate nucleus	UBERON:0001873	82.54	gold quality
pituitary gland	UBERON:0000007	82.49	gold quality
right frontal lobe	UBERON:0002810	82.23	gold quality
brain	UBERON:0000955	82.16	gold quality
adenohypophysis	UBERON:0002196	82.02	gold quality
temporal lobe	UBERON:0001871	81.92	gold quality
amygdala	UBERON:0001876	81.87	gold quality
cerebral cortex	UBERON:0000956	81.65	gold quality
right ovary	UBERON:0002118	81.34	gold quality
right uterine tube	UBERON:0001302	81.22	gold quality
Ammon’s horn	UBERON:0001954	81.20	gold quality
frontal cortex	UBERON:0001870	81.09	gold quality
left ovary	UBERON:0002119	80.85	gold quality
hypothalamus	UBERON:0001898	80.68	gold quality
substantia nigra	UBERON:0002038	80.50	gold quality
prefrontal cortex	UBERON:0000451	80.48	gold quality
ovary	UBERON:0000992	80.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.40

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.