SNHG27

Summary

SNHG27 (small nucleolar RNA host gene 27, HGNC:53481) is a long non-coding RNA gene on chromosome 4q28.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53481
Approved symbol	SNHG27
Name	small nucleolar RNA host gene 27
Location	4q28.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251676
Ensembl biotype	lncRNA
Entrez	101927305
RNAcentral	URS00007E4A15 — lncRNA, 664 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 31 lncRNA

ENST00000507332, ENST00000507933, ENST00000514222, ENST00000653283, ENST00000654278, ENST00000655257, ENST00000657219, ENST00000657220, ENST00000657961, ENST00000658913, ENST00000662181, ENST00000663369, ENST00000663882, ENST00000664137, ENST00000664412, ENST00000667068, ENST00000756843, ENST00000756844, ENST00000756845, ENST00000756846, ENST00000756847, ENST00000756848, ENST00000756849, ENST00000756850, ENST00000756851, ENST00000756852, ENST00000756853, ENST00000756854, ENST00000756855, ENST00000756856, ENST00000756857

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507332 — 2 exons

Exon	Start	End
ENSE00002024313	131791210	131791482
ENSE00002029519	131773565	131773692

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 94.25.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	94.25	gold quality
left testis	UBERON:0004533	94.10	gold quality
testis	UBERON:0000473	93.02	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.52	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.79	gold quality
sural nerve	UBERON:0015488	79.36	gold quality
lower esophagus mucosa	UBERON:0035834	74.17	gold quality
corpus callosum	UBERON:0002336	69.28	gold quality
colonic epithelium	UBERON:0000397	68.22	silver quality
calcaneal tendon	UBERON:0003701	66.74	gold quality
ganglionic eminence	UBERON:0004023	65.78	gold quality
esophagus mucosa	UBERON:0002469	65.62	gold quality
ventricular zone	UBERON:0003053	65.22	gold quality
bone marrow cell	CL:0002092	64.64	silver quality
cortical plate	UBERON:0005343	64.31	gold quality
tibial nerve	UBERON:0001323	63.61	gold quality
skin of leg	UBERON:0001511	63.07	gold quality
vagina	UBERON:0000996	62.43	gold quality
endometrium	UBERON:0001295	62.38	gold quality
zone of skin	UBERON:0000014	62.35	gold quality
superior frontal gyrus	UBERON:0002661	62.15	gold quality
ectocervix	UBERON:0012249	61.90	gold quality
skin of abdomen	UBERON:0001416	61.24	gold quality
esophagus	UBERON:0001043	60.88	gold quality
body of pancreas	UBERON:0001150	60.65	gold quality
right adrenal gland	UBERON:0001233	60.53	gold quality
right uterine tube	UBERON:0001302	60.20	gold quality
right adrenal gland cortex	UBERON:0035827	60.17	gold quality
cortex of kidney	UBERON:0001225	60.10	gold quality
uterine cervix	UBERON:0000002	60.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.