SNHG28

Summary

SNHG28 (small nucleolar RNA host gene 28, HGNC:27647) is a long non-coding RNA gene on chromosome 1q23.2.

Enables RNA binding activity.

Source: NCBI Gene 284677 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27647
Approved symbol	SNHG28
Name	small nucleolar RNA host gene 28
Location	1q23.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ39187, VSIG8-OT1
Ensembl gene	ENSG00000188004
Ensembl biotype	lncRNA
Entrez	284677
RNAcentral	URS0000BC444F — lncRNA, 2190 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000491974, ENST00000621242, ENST00000644477, ENST00000674603, ENST00000674683, ENST00000674714, ENST00000674760, ENST00000674800, ENST00000674808, ENST00000674833, ENST00000674922, ENST00000674949, ENST00000675103, ENST00000675192, ENST00000675285, ENST00000675457, ENST00000675503, ENST00000675556, ENST00000675704, ENST00000675716, ENST00000675766, ENST00000675823, ENST00000676072, ENST00000676093, ENST00000676131, ENST00000676197, ENST00000676249, ENST00000676285, ENST00000676338

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000491974 — 3 exons

Exon	Start	End
ENSE00003606850	159837917	159838027
ENSE00003899881	159854757	159855030
ENSE00003902840	159834523	159836155

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 85.40.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9500 / max 33.0407, expressed in 384 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
15421	0.7684	325
15422	0.1815	95

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	85.40	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.51	gold quality
right uterine tube	UBERON:0001302	82.18	gold quality
prefrontal cortex	UBERON:0000451	81.42	gold quality
frontal cortex	UBERON:0001870	80.87	gold quality
right frontal lobe	UBERON:0002810	80.50	gold quality
cerebellar hemisphere	UBERON:0002245	80.40	gold quality
cerebellar cortex	UBERON:0002129	80.24	gold quality
right hemisphere of cerebellum	UBERON:0014890	80.17	gold quality
cerebellum	UBERON:0002037	80.12	gold quality
cerebral cortex	UBERON:0000956	79.69	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	79.46	gold quality
nucleus accumbens	UBERON:0001882	79.35	gold quality
anterior cingulate cortex	UBERON:0009835	79.17	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.99	gold quality
caudate nucleus	UBERON:0001873	78.72	gold quality
brain	UBERON:0000955	78.67	gold quality
temporal lobe	UBERON:0001871	78.65	gold quality
amygdala	UBERON:0001876	78.57	gold quality
putamen	UBERON:0001874	78.35	gold quality
primary visual cortex	UBERON:0002436	78.32	gold quality
Ammon’s horn	UBERON:0001954	78.00	gold quality
hypothalamus	UBERON:0001898	77.73	gold quality
superior frontal gyrus	UBERON:0002661	77.57	gold quality
substantia nigra	UBERON:0002038	77.14	gold quality
apex of heart	UBERON:0002098	75.43	gold quality
pituitary gland	UBERON:0000007	74.75	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	74.61	gold quality
adenohypophysis	UBERON:0002196	74.43	gold quality
right coronary artery	UBERON:0001625	73.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.