SNHG32

Summary

SNHG32 (small nucleolar RNA host gene 32, HGNC:19078) is a long non-coding RNA gene on chromosome 6p21.33.

Predicted to enable double-stranded RNA binding activity. Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 50854 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:19078
Approved symbol	SNHG32
Name	small nucleolar RNA host gene 32
Location	6p21.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	D6S57, G8
Ensembl gene	ENSG00000204387
Ensembl biotype	lncRNA
OMIM	605447
Entrez	50854
RNAcentral	URS0000E60A00 — lncRNA, 704 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000375633, ENST00000375635, ENST00000375638, ENST00000375640, ENST00000375641, ENST00000375642, ENST00000395788, ENST00000395789, ENST00000614363, ENST00000648677, ENST00000649802, ENST00000718216, ENST00000718217, ENST00000718218, ENST00000718219, ENST00000718220, ENST00000718221, ENST00000718222, ENST00000718223, ENST00000718224, ENST00000718225, ENST00000718226, ENST00000718227, ENST00000718228, ENST00000718229, ENST00000718230, ENST00000718231

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000375633 — 3 exons

Exon	Start	End
ENSE00001467727	31835288	31835451
ENSE00001780717	31839543	31839764
ENSE00003895579	31837236	31837435

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 99.46.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 117.3618 / max 926.3578, expressed in 1824 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
67069	115.7859	1824
67068	0.8575	399
203947	0.6297	365
67074	0.0887	39

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left ovary	UBERON:0002119	99.46	gold quality
ovary	UBERON:0000992	99.38	gold quality
right ovary	UBERON:0002118	99.37	gold quality
endocervix	UBERON:0000458	99.27	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	99.08	gold quality
body of uterus	UBERON:0009853	99.07	gold quality
stromal cell of endometrium	CL:0002255	98.94	gold quality
thyroid gland	UBERON:0002046	98.90	gold quality
left lobe of thyroid gland	UBERON:0001120	98.89	gold quality
uterine cervix	UBERON:0000002	98.84	gold quality
left testis	UBERON:0004533	98.84	gold quality
ectocervix	UBERON:0012249	98.82	gold quality
right lobe of thyroid gland	UBERON:0001119	98.80	gold quality
right testis	UBERON:0004534	98.80	gold quality
myometrium	UBERON:0001296	98.68	gold quality
body of pancreas	UBERON:0001150	98.66	gold quality
substantia nigra	UBERON:0002038	98.65	gold quality
fallopian tube	UBERON:0003889	98.62	gold quality
left uterine tube	UBERON:0001303	98.61	gold quality
thoracic mammary gland	UBERON:0005200	98.61	gold quality
amygdala	UBERON:0001876	98.59	gold quality
metanephros cortex	UBERON:0010533	98.59	gold quality
temporal lobe	UBERON:0001871	98.54	gold quality
mucosa of stomach	UBERON:0001199	98.52	gold quality
prostate gland	UBERON:0002367	98.52	gold quality
vagina	UBERON:0000996	98.50	gold quality
right coronary artery	UBERON:0001625	98.49	gold quality
cortical plate	UBERON:0005343	98.49	gold quality
right lung	UBERON:0002167	98.47	gold quality
nucleus accumbens	UBERON:0001882	98.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	13.56

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Single nucleotide polymorphisms at C6orf48, BAT2 and ZBTB12 are associated with estrogen receptor positive breast cancer in the Chinese Han population. (PMID:23079975)
• Long non-coding RNA SNHG3 promotes progression of gastric cancer by regulating neighboring MED18 gene methylation. (PMID:31534128)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.