SNHG33

Summary

SNHG33 (small nucleolar RNA host gene 33, HGNC:48575) is a unprocessed pseudogene on chromosome 3q27.1.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48575
Approved symbol	SNHG33
Name	small nucleolar RNA host gene 33
Location	3q27.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	PAINT
Ensembl gene	ENSG00000240024
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	100505687
RNAcentral	URS000075D97B — lncRNA, 1644 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000487386

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000487386 — 4 exons

Exon	Start	End
ENSE00001825264	183452371	183452485
ENSE00001857517	183454015	183454093
ENSE00001900699	183451741	183451822
ENSE00001949081	183455191	183455335

Expression profiles

Bgee: expression breadth ubiquitous, 244 present calls, max score 93.15.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 6.3523 / max 67.3365, expressed in 1571 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
40102	5.0267	1464
40101	1.3256	735

Top tissues by expression

253 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
Brodmann (1909) area 23	UBERON:0013554	93.15	gold quality
endothelial cell	CL:0000115	92.76	gold quality
substantia nigra pars compacta	UBERON:0001965	90.75	gold quality
middle temporal gyrus	UBERON:0002771	90.71	gold quality
vastus lateralis	UBERON:0001379	90.60	gold quality
biceps brachii	UBERON:0001507	90.57	gold quality
adrenal tissue	UBERON:0018303	89.61	gold quality
quadriceps femoris	UBERON:0001377	89.47	gold quality
substantia nigra pars reticulata	UBERON:0001966	89.42	gold quality
primary visual cortex	UBERON:0002436	89.08	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	88.70	gold quality
lateral nuclear group of thalamus	UBERON:0002736	88.69	gold quality
nucleus accumbens	UBERON:0001882	88.47	gold quality
right adrenal gland cortex	UBERON:0035827	88.44	gold quality
left adrenal gland	UBERON:0001234	88.12	gold quality
occipital lobe	UBERON:0002021	88.01	gold quality
epithelial cell of pancreas	CL:0000083	87.95	gold quality
buccal mucosa cell	CL:0002336	87.95	gold quality
cerebellar vermis	UBERON:0004720	87.92	gold quality
adrenal gland	UBERON:0002369	87.87	gold quality
hypothalamus	UBERON:0001898	87.85	gold quality
right adrenal gland	UBERON:0001233	87.78	gold quality
adrenal cortex	UBERON:0001235	87.66	gold quality
left adrenal gland cortex	UBERON:0035825	87.48	gold quality
heart right ventricle	UBERON:0002080	87.42	gold quality
deltoid	UBERON:0001476	87.36	gold quality
tibia	UBERON:0000979	86.90	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	86.83	gold quality
pons	UBERON:0000988	86.61	gold quality
substantia nigra	UBERON:0002038	86.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.10

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Long-chain non-coding RNA Linc00888 promotes the proliferation and migration of esophageal cancer cells by downregulating miR-34a expression. (PMID:33215424)
• LncRNA LINC00888 upregulation predicts a worse survival of laryngeal cancer patients and accelerates the growth and mobility of laryngeal cancer cells through regulation of miR-378g/TFRC. (PMID:34472153)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.