SNORA104

Summary

SNORA104 (small nucleolar RNA, H/ACA box 104, HGNC:51396) is a gene on chromosome 19p13.12.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51396
Approved symbol	SNORA104
Name	small nucleolar RNA, H/ACA box 104
Location	19p13.12
Locus type	RNA, small nucleolar
Status	Approved
Entrez	106635534
RNAcentral	URS00008E3967 — snoRNA, 139 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000357545 (19:14621801 T>G), RS1000813495 (19:14621312 G>A,T), RS1001270753 (19:14622410 A>G), RS1001293506 (19:14620769 T>C), RS1005174275 (19:14622537 T>C), RS1009957218 (19:14621294 A>C,G), RS1010345379 (19:14621059 G>A), RS1018922626 (19:14621887 A>G), RS1018974520 (19:14621348 G>A,C), RS1020378133 (19:14621296 T>C), RS1020420713 (19:14621084 A>C), RS1026669477 (19:14620746 C>G), RS1026844263 (19:14620281 A>G), RS1027846890 (19:14622434 A>G), RS1027909140 (19:14621178 C>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Air Pollutants	decreases expression, increases abundance	1
Smoke	increases expression	1
Particulate Matter	decreases expression, increases abundance	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.