SNORA109

Summary

SNORA109 (small nucleolar RNA, H/ACA box 109, HGNC:51402) is a gene on chromosome Xp11.21.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51402
Approved symbol	SNORA109
Name	small nucleolar RNA, H/ACA box 109
Location	Xp11.21
Locus type	RNA, small nucleolar
Status	Approved
Entrez	106635544
RNAcentral	URS00008E39C3 — snoRNA, 128 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1005102613 (X:55183638 A>G), RS1005176092 (X:55183967 T>A), RS1005245610 (X:55185518 G>A), RS1006197631 (X:55184094 C>T), RS1006250214 (X:55183729 C>G,T), RS1009811331 (X:55185016 A>T), RS1009864095 (X:55184652 T>C), RS1010224735 (X:55184657 G>T), RS1011767318 (X:55184382 G>A), RS1012671926 (X:55183467 C>T), RS1013652657 (X:55184467 G>A), RS1014121232 (X:55184130 G>A), RS1014924018 (X:55184101 T>A), RS1015029040 (X:55183428 A>C), RS1015134640 (X:55183650 C>T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

2 total (human), top 2 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Air Pollutants	increases abundance, decreases expression	1
Particulate Matter	decreases expression, increases abundance	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.