SNORA11

Summary

SNORA11 (small nucleolar RNA, H/ACA box 11, HGNC:32599) is a small nucleolar RNA gene on chromosome Xp11.21.

Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA11, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).

Source: NCBI Gene 677799 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32599
Approved symbol	SNORA11
Name	small nucleolar RNA, H/ACA box 11
Location	Xp11.21
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U107, SNORA11A
Ensembl gene	ENSG00000221716
Ensembl biotype	snoRNA
OMIM	300662
Entrez	677799
RNAcentral	URS000032FEC4 — snoRNA, 131 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000408789

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000408789 — 1 exons

Exon	Start	End
ENSE00001565424	54814370	54814497

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 99.79.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.79	gold quality
adrenal tissue	UBERON:0018303	96.94	gold quality
left ovary	UBERON:0002119	91.77	gold quality
pituitary gland	UBERON:0000007	91.18	gold quality
right ovary	UBERON:0002118	91.01	gold quality
ovary	UBERON:0000992	90.87	gold quality
adenohypophysis	UBERON:0002196	89.46	gold quality
metanephros cortex	UBERON:0010533	89.14	gold quality
descending thoracic aorta	UBERON:0002345	88.56	gold quality
cortex of kidney	UBERON:0001225	87.92	gold quality
right uterine tube	UBERON:0001302	87.91	gold quality
endocervix	UBERON:0000458	87.85	gold quality
left testis	UBERON:0004533	87.72	gold quality
testis	UBERON:0000473	86.92	gold quality
right coronary artery	UBERON:0001625	86.59	gold quality
right testis	UBERON:0004534	86.26	gold quality
hindlimb stylopod muscle	UBERON:0004252	86.06	gold quality
granulocyte	CL:0000094	85.88	gold quality
ascending aorta	UBERON:0001496	85.38	gold quality
thoracic aorta	UBERON:0001515	85.33	gold quality
left lobe of thyroid gland	UBERON:0001120	85.30	gold quality
kidney	UBERON:0002113	85.08	gold quality
body of uterus	UBERON:0009853	84.99	gold quality
right lobe of thyroid gland	UBERON:0001119	84.86	gold quality
myometrium	UBERON:0001296	84.71	gold quality
thyroid gland	UBERON:0002046	84.24	gold quality
bone marrow	UBERON:0002371	84.24	gold quality
prostate gland	UBERON:0002367	83.74	gold quality
hypothalamus	UBERON:0001898	83.37	gold quality
left coronary artery	UBERON:0001626	83.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.88

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (10): (ENSG00000221060), SNORA11B (ENSG00000221102), SNORA11F (ENSG00000221164), (ENSG00000221245), (ENSG00000221398), SNORA11C (ENSG00000221459), SNORA11D (ENSG00000221475), SNORA11E (ENSG00000221705), SNORA11G (ENSG00000221750), (ENSG00000261709)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.