SNORA23

Summary

SNORA23 (small nucleolar RNA, H/ACA box 23, HGNC:32613) is a small nucleolar RNA gene on chromosome 11p15.4.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677808 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32613
Approved symbol	SNORA23
Name	small nucleolar RNA, H/ACA box 23
Location	11p15.4
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA23
Ensembl gene	ENSG00000201998
Ensembl biotype	snoRNA
Entrez	677808
RNAcentral	URS0000818C5D — snoRNA, 189 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000365128

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000365128 — 1 exons

Exon	Start	End
ENSE00001439891	9428773	9428954

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 99.76.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5652 / max 41.6971, expressed in 292 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
112972	0.5652	292

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.76	gold quality
adrenal tissue	UBERON:0018303	99.65	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	98.89	gold quality
corpus callosum	UBERON:0002336	97.95	gold quality
calcaneal tendon	UBERON:0003701	93.30	gold quality
hindlimb stylopod muscle	UBERON:0004252	86.35	gold quality
ganglionic eminence	UBERON:0004023	83.72	gold quality
liver	UBERON:0002107	78.68	gold quality
blood	UBERON:0000178	76.38	gold quality
monocyte	CL:0000576	75.74	gold quality
kidney	UBERON:0002113	75.41	gold quality
prefrontal cortex	UBERON:0000451	74.53	gold quality
primary visual cortex	UBERON:0002436	73.90	gold quality
skeletal muscle tissue	UBERON:0001134	72.95	gold quality
endometrium	UBERON:0001295	72.31	gold quality
lung	UBERON:0002048	72.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.96	gold quality
muscle of leg	UBERON:0001383	70.64	gold quality
islet of Langerhans	UBERON:0000006	70.56	gold quality
stomach	UBERON:0000945	69.97	gold quality
adult mammalian kidney	UBERON:0000082	69.94	gold quality
superior frontal gyrus	UBERON:0002661	69.83	gold quality
vermiform appendix	UBERON:0001154	69.54	gold quality
gastrocnemius	UBERON:0001388	68.93	gold quality
placenta	UBERON:0001987	68.72	gold quality
ascending aorta	UBERON:0001496	68.57	gold quality
heart	UBERON:0000948	68.29	gold quality
uterine cervix	UBERON:0000002	68.26	gold quality
thoracic aorta	UBERON:0001515	68.06	gold quality
ectocervix	UBERON:0012249	67.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• The present study demonstrates the involvement of SNORA23 overexpression in the aggressive phenotypes of invasion, anchor-independent survival, and metastasis of PDAC cells. (PMID:28390868)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	SNORA23	ENSDARG00000082611
mus_musculus	Snora23	ENSMUSG00000064451
rattus_norvegicus	Snora23	ENSRNOG00000057923

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.