SNORA24

Summary

SNORA24 (small nucleolar RNA, H/ACA box 24, HGNC:32614) is a small nucleolar RNA gene on chromosome 4q26.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677809 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32614
Approved symbol	SNORA24
Name	small nucleolar RNA, H/ACA box 24
Location	4q26
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA24, SNORA24A
Ensembl gene	ENSG00000275994
Ensembl biotype	snoRNA
Entrez	677809
RNAcentral	URS000029D639 — snoRNA, 131 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384096

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384096 — 1 exons

Exon	Start	End
ENSE00001808173	118279190	118279320

Expression profiles

Bgee: expression breadth broad, 25 present calls, max score 99.77.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1222 / max 27.2690, expressed in 35 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
49422	0.1222	35

Top tissues by expression

25 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.77	gold quality
liver	UBERON:0002107	99.51	gold quality
stomach	UBERON:0000945	96.91	gold quality
colon	UBERON:0001155	96.56	gold quality
intestine	UBERON:0000160	95.06	gold quality
adult mammalian kidney	UBERON:0000082	93.99	gold quality
lung	UBERON:0002048	93.89	gold quality
adrenal tissue	UBERON:0018303	92.78	gold quality
kidney	UBERON:0002113	92.77	gold quality
anterior cingulate cortex	UBERON:0009835	87.93	gold quality
blood	UBERON:0000178	84.63	gold quality
heart	UBERON:0000948	83.89	gold quality
upper lobe of left lung	UBERON:0008952	82.22	gold quality
left lobe of thyroid gland	UBERON:0001120	79.41	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.04	gold quality
gastrocnemius	UBERON:0001388	77.46	gold quality
tibial artery	UBERON:0007610	76.88	gold quality
skin of leg	UBERON:0001511	72.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.16	gold quality
muscle of leg	UBERON:0001383	69.32	gold quality
calcaneal tendon	UBERON:0003701	68.12	gold quality
myometrium	UBERON:0001296	66.64	gold quality
monocyte	CL:0000576	61.62	gold quality
Ammon’s horn	UBERON:0001954	61.41	gold quality
heart left ventricle	UBERON:0002084	50.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• From a clinical perspective, the authors further show that human hepatocellular carcinomas with low SNORA24 expression display increased lipid content and are associated with poor patient survival. (PMID:31478838)
• Involvement of the oncogenic small nucleolar RNA SNORA24 in regulation of p53 stability in colorectal cancer. (PMID:36087186)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snora24	ENSMUSG00000092730
rattus_norvegicus	LOC120100362	ENSRNOG00000052644
rattus_norvegicus	LOC120101240	ENSRNOG00000053898

Paralogs (2): SNORA24B (ENSG00000206903), (ENSG00000207130)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.