SNORA2B

Summary

SNORA2B (small nucleolar RNA, H/ACA box 2B, HGNC:32585) is a small nucleolar RNA gene on chromosome 12q13.11.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677794 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32585
Approved symbol	SNORA2B
Name	small nucleolar RNA, H/ACA box 2B
Location	12q13.11
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA2b
Ensembl gene	ENSG00000207313
Ensembl biotype	snoRNA
Entrez	677794
RNAcentral	URS0000599BEA — snoRNA, 137 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384583

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384583 — 1 exons

Exon	Start	End
ENSE00001499591	48667457	48667593

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 99.22.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	99.22	gold quality
sural nerve	UBERON:0015488	99.09	gold quality
adrenal tissue	UBERON:0018303	91.81	gold quality
hindlimb stylopod muscle	UBERON:0004252	89.60	gold quality
monocyte	CL:0000576	85.71	gold quality
liver	UBERON:0002107	84.04	gold quality
bone marrow	UBERON:0002371	83.14	gold quality
kidney	UBERON:0002113	82.41	gold quality
adult mammalian kidney	UBERON:0000082	79.70	gold quality
prefrontal cortex	UBERON:0000451	79.39	gold quality
endometrium	UBERON:0001295	77.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.02	gold quality
blood	UBERON:0000178	76.90	gold quality
corpus callosum	UBERON:0002336	76.78	gold quality
islet of Langerhans	UBERON:0000006	74.43	gold quality
placenta	UBERON:0001987	73.67	gold quality
vermiform appendix	UBERON:0001154	73.66	gold quality
stomach	UBERON:0000945	72.84	gold quality
calcaneal tendon	UBERON:0003701	72.69	gold quality
left uterine tube	UBERON:0001303	72.24	gold quality
fallopian tube	UBERON:0003889	71.33	gold quality
pancreas	UBERON:0001264	71.27	gold quality
muscle of leg	UBERON:0001383	71.27	gold quality
lung	UBERON:0002048	71.23	gold quality
rectum	UBERON:0001052	70.96	gold quality
gastrocnemius	UBERON:0001388	70.74	gold quality
cortex of kidney	UBERON:0001225	70.66	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.16	gold quality
heart	UBERON:0000948	70.04	gold quality
gall bladder	UBERON:0002110	69.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.35

Regulation

Is transcription factor: no

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm22704	ENSMUSG00000064961
mus_musculus	Snora2b	ENSMUSG00000065939
rattus_norvegicus	LOC120102638	ENSRNOG00000054530
rattus_norvegicus	Snora2b	ENSRNOG00000063116
rattus_norvegicus		ENSRNOG00000077067

Paralogs (5): (ENSG00000199959), (ENSG00000202343), SNORA2A (ENSG00000206612), (ENSG00000206647), SNORA2C (ENSG00000221491)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.