SNORA33

Summary

SNORA33 (small nucleolar RNA, H/ACA box 33, HGNC:32623) is a small nucleolar RNA gene on chromosome 6q23.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 594839 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32623
Approved symbol	SNORA33
Name	small nucleolar RNA, H/ACA box 33
Location	6q23.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA33
Ensembl gene	ENSG00000200534
Ensembl biotype	snoRNA
Entrez	594839
RNAcentral	URS00005A3020 — snoRNA, 133 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000363664

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363664 — 1 exons

Exon	Start	End
ENSE00001438427	132817219	132817348

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 99.38.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 1199.4884 / max 18681.0589, expressed in 1828 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
69829	1199.4884	1828

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.38	gold quality
lower esophagus mucosa	UBERON:0035834	99.24	gold quality
granulocyte	CL:0000094	98.71	gold quality
right uterine tube	UBERON:0001302	98.18	gold quality
adrenal tissue	UBERON:0018303	98.05	gold quality
right ovary	UBERON:0002118	97.95	gold quality
left ovary	UBERON:0002119	97.92	gold quality
ectocervix	UBERON:0012249	97.84	gold quality
left uterine tube	UBERON:0001303	97.60	gold quality
mucosa of transverse colon	UBERON:0004991	97.56	gold quality
endocervix	UBERON:0000458	97.54	gold quality
vagina	UBERON:0000996	97.48	gold quality
ovary	UBERON:0000992	97.21	gold quality
prostate gland	UBERON:0002367	97.20	gold quality
tibial nerve	UBERON:0001323	97.10	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	97.09	gold quality
omental fat pad	UBERON:0010414	96.62	gold quality
body of uterus	UBERON:0009853	96.54	gold quality
right lobe of thyroid gland	UBERON:0001119	96.49	gold quality
right lobe of liver	UBERON:0001114	96.41	gold quality
spleen	UBERON:0002106	96.30	gold quality
metanephros cortex	UBERON:0010533	96.29	gold quality
right lung	UBERON:0002167	96.22	gold quality
esophagus mucosa	UBERON:0002469	96.09	gold quality
endometrium	UBERON:0001295	95.98	gold quality
left lobe of thyroid gland	UBERON:0001120	95.97	gold quality
minor salivary gland	UBERON:0001830	95.93	gold quality
upper lobe of left lung	UBERON:0008952	95.72	gold quality
adenohypophysis	UBERON:0002196	95.69	gold quality
myometrium	UBERON:0001296	95.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.55

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Depletion of SNORA33 Abolishes psi of 28S-U4966 and Affects the Ribosome Translational Apparatus. (PMID:37628759)

Cross-species orthologs

0 orthologs

Paralogs (3): (ENSG00000201827), (ENSG00000202283), (ENSG00000252045)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.