SNORA36A

Summary

SNORA36A (small nucleolar RNA, H/ACA box 36A, HGNC:32628) is a small nucleolar RNA gene on chromosome Xq28.

Biosynthesis of stable cellular RNAs such as tRNAs, rRNAs, snRNAs, and snoRNAs is aided by covalent nucleotide modification after transcription. The modified nucleotides are involved in correct RNA folding, establishment of correct RNA-RNA and RNA-protein interactions, and in the correct function of mature RNAs. The RNA encoded by this gene is thought to mediate the pseudouridylation of residues U105 and U1244 of 18S rRNA.

Source: NCBI Gene 677817 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32628
Approved symbol	SNORA36A
Name	small nucleolar RNA, H/ACA box 36A
Location	Xq28
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA36
Ensembl gene	ENSG00000206948
Ensembl biotype	snoRNA
Entrez	677817
RNAcentral	URS000061AA47 — snoRNA, 132 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384221

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384221 — 1 exons

Exon	Start	End
ENSE00001807652	154768528	154768659

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 99.81.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.81	gold quality
liver	UBERON:0002107	82.63	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	79.07	gold quality
adrenal tissue	UBERON:0018303	79.02	gold quality
monocyte	CL:0000576	78.63	gold quality
bone marrow	UBERON:0002371	78.56	gold quality
calcaneal tendon	UBERON:0003701	77.83	gold quality
ectocervix	UBERON:0012249	77.44	gold quality
granulocyte	CL:0000094	75.98	gold quality
islet of Langerhans	UBERON:0000006	74.83	gold quality
vermiform appendix	UBERON:0001154	74.74	gold quality
adult mammalian kidney	UBERON:0000082	74.33	gold quality
kidney	UBERON:0002113	73.96	gold quality
blood	UBERON:0000178	73.10	gold quality
endometrium	UBERON:0001295	73.05	gold quality
duodenum	UBERON:0002114	72.29	gold quality
muscle of leg	UBERON:0001383	72.21	gold quality
right lung	UBERON:0002167	71.98	gold quality
lymph node	UBERON:0000029	71.55	gold quality
lung	UBERON:0002048	71.06	gold quality
gastrocnemius	UBERON:0001388	70.93	gold quality
urinary bladder	UBERON:0001255	70.74	gold quality
right lobe of liver	UBERON:0001114	70.16	gold quality
left ovary	UBERON:0002119	70.05	gold quality
endocervix	UBERON:0000458	69.87	gold quality
ovary	UBERON:0000992	69.58	gold quality
body of pancreas	UBERON:0001150	69.50	gold quality
stomach	UBERON:0000945	69.22	gold quality
left coronary artery	UBERON:0001626	68.65	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (4): (ENSG00000200294), (ENSG00000206731), SNORA36C (ENSG00000207016), SNORA36B (ENSG00000222370)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.