SNORA3B

Summary

SNORA3B (small nucleolar RNA, H/ACA box 3B, HGNC:32638) is a small nucleolar RNA gene on chromosome 11p15.4.

Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).

Source: NCBI Gene 677826 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32638
Approved symbol	SNORA3B
Name	small nucleolar RNA, H/ACA box 3B
Location	11p15.4
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA3-2
Ensembl gene	ENSG00000212607
Ensembl biotype	snoRNA
OMIM	611333
Entrez	677826
RNAcentral	URS0000451E99 — snoRNA, 131 nt, 6 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000391305

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000391305 — 1 exons

Exon	Start	End
ENSE00001509089	8685439	8685569

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 99.76.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.76	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	97.79	gold quality
adrenal tissue	UBERON:0018303	96.45	gold quality
lower esophagus mucosa	UBERON:0035834	94.79	gold quality
granulocyte	CL:0000094	94.75	gold quality
monocyte	CL:0000576	91.38	gold quality
leukocyte	CL:0000738	91.25	gold quality
mucosa of transverse colon	UBERON:0004991	90.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	90.04	gold quality
left uterine tube	UBERON:0001303	88.19	gold quality
hindlimb stylopod muscle	UBERON:0004252	88.15	gold quality
bone marrow	UBERON:0002371	88.10	gold quality
liver	UBERON:0002107	88.02	gold quality
vagina	UBERON:0000996	87.27	gold quality
lung	UBERON:0002048	86.87	gold quality
right uterine tube	UBERON:0001302	86.69	gold quality
adenohypophysis	UBERON:0002196	86.53	gold quality
mucosa of stomach	UBERON:0001199	86.51	gold quality
prostate gland	UBERON:0002367	86.46	gold quality
spleen	UBERON:0002106	86.44	gold quality
skin of abdomen	UBERON:0001416	86.35	gold quality
pituitary gland	UBERON:0000007	86.21	gold quality
upper lobe of left lung	UBERON:0008952	86.20	gold quality
ectocervix	UBERON:0012249	86.15	gold quality
stomach	UBERON:0000945	86.12	gold quality
left ovary	UBERON:0002119	86.10	gold quality
right lobe of liver	UBERON:0001114	86.03	gold quality
right ovary	UBERON:0002118	85.91	gold quality
blood	UBERON:0000178	85.62	gold quality
body of stomach	UBERON:0001161	85.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.10

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm24888	ENSMUSG00000077575
rattus_norvegicus	Snora3B	ENSRNOG00000053089
rattus_norvegicus		ENSRNOG00000053692

Paralogs (6): SNORA3A (ENSG00000200983), (ENSG00000221093), (ENSG00000221148), (ENSG00000221639), SNORA3C (ENSG00000221719), (ENSG00000251778)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.