SNORA40

Summary

SNORA40 (small nucleolar RNA, H/ACA box 40, HGNC:32633) is a small nucleolar RNA gene on chromosome 11q21.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677822 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32633
Approved symbol	SNORA40
Name	small nucleolar RNA, H/ACA box 40
Location	11q21
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA40, SNORA40A
Ensembl gene	ENSG00000210825
Ensembl biotype	snoRNA
Entrez	677822
RNAcentral	URS00002587B6 — snoRNA, 127 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000388090

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000388090 — 1 exons

Exon	Start	End
ENSE00001503096	93735111	93735236

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 99.71.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0960 / max 23.6810, expressed in 13 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
121833	0.0960	13

Top tissues by expression

34 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adult mammalian kidney	UBERON:0000082	99.71	gold quality
sural nerve	UBERON:0015488	99.60	gold quality
liver	UBERON:0002107	99.26	gold quality
colon	UBERON:0001155	98.89	gold quality
kidney	UBERON:0002113	97.33	gold quality
adrenal tissue	UBERON:0018303	96.84	gold quality
intestine	UBERON:0000160	96.63	gold quality
stomach	UBERON:0000945	93.03	gold quality
lung	UBERON:0002048	92.20	gold quality
heart	UBERON:0000948	88.89	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.62	gold quality
anterior cingulate cortex	UBERON:0009835	85.81	gold quality
hypothalamus	UBERON:0001898	81.84	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.91	gold quality
left coronary artery	UBERON:0001626	77.18	gold quality
blood	UBERON:0000178	73.35	gold quality
gastrocnemius	UBERON:0001388	70.97	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	70.80	gold quality
tibial artery	UBERON:0007610	69.77	gold quality
cerebellar hemisphere	UBERON:0002245	69.56	gold quality
islet of Langerhans	UBERON:0000006	68.90	gold quality
muscle of leg	UBERON:0001383	68.68	gold quality
monocyte	CL:0000576	68.37	gold quality
body of pancreas	UBERON:0001150	68.09	gold quality
adipose tissue	UBERON:0001013	64.97	gold quality
skin of leg	UBERON:0001511	64.91	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.18	gold quality
putamen	UBERON:0001874	63.25	gold quality
thyroid gland	UBERON:0002046	61.48	gold quality
right lobe of thyroid gland	UBERON:0001119	60.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (21): SNORA40B (ENSG00000208308), (ENSG00000212134), (ENSG00000212149), (ENSG00000212266), (ENSG00000212273), (ENSG00000212363), (ENSG00000212455), (ENSG00000212579), SNORA40C (ENSG00000212587), (ENSG00000222966), (ENSG00000251704), (ENSG00000252049), (ENSG00000252083), (ENSG00000252138), (ENSG00000252188), (ENSG00000252352), (ENSG00000252693), (ENSG00000253047), (ENSG00000253065), (ENSG00000273499), (ENSG00000274458)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.