SNORA50B

Summary

SNORA50B (small nucleolar RNA, H/ACA box 50B, HGNC:50432) is a small nucleolar RNA gene on chromosome 22q12.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109616998 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50432
Approved symbol	SNORA50B
Name	small nucleolar RNA, H/ACA box 50B
Location	22q12.3
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000253007
Ensembl biotype	snoRNA
Entrez	109616998
RNAcentral	URS00006CD075 — snoRNA, 135 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000517198

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517198 — 1 exons

Exon	Start	End
ENSE00002089475	33704786	33704920

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 90.53.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	90.53	gold quality
stomach	UBERON:0000945	89.64	gold quality
adult mammalian kidney	UBERON:0000082	88.31	gold quality
kidney	UBERON:0002113	84.41	gold quality
adrenal tissue	UBERON:0018303	81.40	gold quality
blood	UBERON:0000178	79.39	gold quality
lung	UBERON:0002048	79.06	gold quality
calcaneal tendon	UBERON:0003701	78.49	gold quality
islet of Langerhans	UBERON:0000006	73.69	gold quality
intestine	UBERON:0000160	73.33	gold quality
heart	UBERON:0000948	72.45	gold quality
body of stomach	UBERON:0001161	70.85	gold quality
myometrium	UBERON:0001296	69.63	gold quality
gastrocnemius	UBERON:0001388	69.11	gold quality
colon	UBERON:0001155	68.48	gold quality
body of pancreas	UBERON:0001150	67.87	gold quality
tibial artery	UBERON:0007610	67.75	gold quality
minor salivary gland	UBERON:0001830	66.78	gold quality
heart left ventricle	UBERON:0002084	66.30	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.04	gold quality
right atrium auricular region	UBERON:0006631	65.87	gold quality
left ovary	UBERON:0002119	65.73	gold quality
vagina	UBERON:0000996	65.08	gold quality
substantia nigra	UBERON:0002038	64.17	gold quality
nucleus accumbens	UBERON:0001882	64.08	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.03	gold quality
lower esophagus muscularis layer	UBERON:0035833	63.81	gold quality
muscle layer of sigmoid colon	UBERON:0035805	63.70	gold quality
ascending aorta	UBERON:0001496	63.59	gold quality
subcutaneous adipose tissue	UBERON:0002190	63.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (5): SNORA50A (ENSG00000206952), (ENSG00000252122), (ENSG00000252904), SNORA50C (ENSG00000277887), SNORA50D (ENSG00000280894)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.