SNORA51

Summary

SNORA51 (small nucleolar RNA, H/ACA box 51, HGNC:32644) is a small nucleolar RNA gene on chromosome 20p13.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677831 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32644
Approved symbol	SNORA51
Name	small nucleolar RNA, H/ACA box 51
Location	20p13
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA51
Ensembl gene	ENSG00000271798
Ensembl biotype	snoRNA
Entrez	677831
RNAcentral	URS00004F2BDE — snoRNA, 132 nt, 6 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000606420

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606420 — 1 exons

Exon	Start	End
ENSE00003700784	2655067	2655198

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 99.49.

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.49	gold quality
adrenal tissue	UBERON:0018303	93.06	gold quality
granulocyte	CL:0000094	91.08	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.25	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	80.92	gold quality
liver	UBERON:0002107	77.85	gold quality
prefrontal cortex	UBERON:0000451	77.49	gold quality
skeletal muscle tissue	UBERON:0001134	77.14	gold quality
monocyte	CL:0000576	76.59	gold quality
blood	UBERON:0000178	75.41	gold quality
kidney	UBERON:0002113	75.16	gold quality
bone marrow	UBERON:0002371	75.03	gold quality
left uterine tube	UBERON:0001303	74.85	gold quality
calcaneal tendon	UBERON:0003701	74.01	gold quality
fundus of stomach	UBERON:0001160	73.98	gold quality
stomach	UBERON:0000945	73.71	gold quality
endometrium	UBERON:0001295	72.90	gold quality
cortex of kidney	UBERON:0001225	72.69	gold quality
islet of Langerhans	UBERON:0000006	72.40	gold quality
muscle of leg	UBERON:0001383	72.30	gold quality
duodenum	UBERON:0002114	72.16	gold quality
lung	UBERON:0002048	71.99	gold quality
vermiform appendix	UBERON:0001154	71.88	gold quality
gastrocnemius	UBERON:0001388	71.84	gold quality
pancreas	UBERON:0001264	71.75	gold quality
body of pancreas	UBERON:0001150	71.50	gold quality
body of stomach	UBERON:0001161	70.90	gold quality
placenta	UBERON:0001987	70.59	gold quality
adrenal gland	UBERON:0002369	70.58	gold quality
omental fat pad	UBERON:0010414	70.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.62

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• The small nucleolar RNA SNORA51 enhances breast cancer stem cell-like properties via the RPL3/NPM1/c-MYC pathway. (PMID:38421204)

Cross-species orthologs

0 orthologs

Paralogs (12): (ENSG00000200113), (ENSG00000201465), (ENSG00000201516), (ENSG00000201863), (ENSG00000206853), (ENSG00000206878), (ENSG00000206898), (ENSG00000206961), (ENSG00000207022), (ENSG00000207147), (ENSG00000207171), (ENSG00000207177)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.