SNORA52

Summary

SNORA52 (small nucleolar RNA, H/ACA box 52, HGNC:32645) is a small nucleolar RNA gene on chromosome 11p15.5.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 619565 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32645
Approved symbol	SNORA52
Name	small nucleolar RNA, H/ACA box 52
Location	11p15.5
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA52
Ensembl gene	ENSG00000199785
Ensembl biotype	snoRNA
Entrez	619565
RNAcentral	URS00003E7565 — snoRNA, 134 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000362915

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000362915 — 1 exons

Exon	Start	End
ENSE00001437678	811681	811814

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 98.83.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0598 / max 19.3754, expressed in 24 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
112265	0.0598	24

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	98.83	gold quality
sural nerve	UBERON:0015488	98.20	gold quality
blood	UBERON:0000178	81.55	gold quality
omental fat pad	UBERON:0010414	81.14	gold quality
lower esophagus mucosa	UBERON:0035834	80.94	gold quality
skin of abdomen	UBERON:0001416	80.70	gold quality
mucosa of transverse colon	UBERON:0004991	79.98	gold quality
adipose tissue	UBERON:0001013	79.63	gold quality
ectocervix	UBERON:0012249	79.41	gold quality
liver	UBERON:0002107	79.11	gold quality
thoracic mammary gland	UBERON:0005200	79.06	gold quality
left ovary	UBERON:0002119	78.91	gold quality
lung	UBERON:0002048	78.41	gold quality
zone of skin	UBERON:0000014	78.38	gold quality
subcutaneous adipose tissue	UBERON:0002190	78.36	gold quality
stomach	UBERON:0000945	78.02	gold quality
ovary	UBERON:0000992	78.01	gold quality
vagina	UBERON:0000996	77.94	gold quality
mucosa of stomach	UBERON:0001199	77.93	gold quality
body of pancreas	UBERON:0001150	76.87	gold quality
myometrium	UBERON:0001296	76.76	gold quality
skin of leg	UBERON:0001511	76.69	gold quality
right ovary	UBERON:0002118	76.50	gold quality
pancreas	UBERON:0001264	76.09	gold quality
duodenum	UBERON:0002114	76.09	gold quality
tibial nerve	UBERON:0001323	75.99	gold quality
upper lobe of left lung	UBERON:0008952	75.96	gold quality
endocervix	UBERON:0000458	75.95	gold quality
esophagus mucosa	UBERON:0002469	75.81	gold quality
descending thoracic aorta	UBERON:0002345	75.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Downregulation of snoRNA SNORA52 and Its Clinical Significance in Hepatocellular Carcinoma. (PMID:34195281)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snora52	ENSMUSG00000064666
mus_musculus	Gm54463	ENSMUSG00002076417
rattus_norvegicus	Snora52	ENSRNOG00000065361

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.