SNORA57

Summary

SNORA57 (small nucleolar RNA, H/ACA box 57, HGNC:32651) is a small nucleolar RNA gene on chromosome 11q12.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692158 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32651
Approved symbol	SNORA57
Name	small nucleolar RNA, H/ACA box 57
Location	11q12.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U99
Ensembl gene	ENSG00000206597
Ensembl biotype	snoRNA
Entrez	692158
RNAcentral	URS00000CC074 — snoRNA, 149 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000383870

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000383870 — 1 exons

Exon	Start	End
ENSE00001498880	62665422	62665570

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 99.30.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7367 / max 63.8669, expressed in 303 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
114723	0.7367	303

Top tissues by expression

83 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.30	gold quality
adrenal tissue	UBERON:0018303	98.36	gold quality
liver	UBERON:0002107	97.06	gold quality
lung	UBERON:0002048	91.44	gold quality
stomach	UBERON:0000945	86.18	gold quality
blood	UBERON:0000178	83.82	gold quality
kidney	UBERON:0002113	83.76	gold quality
myometrium	UBERON:0001296	82.55	gold quality
adult mammalian kidney	UBERON:0000082	76.57	gold quality
monocyte	CL:0000576	76.07	gold quality
intestine	UBERON:0000160	75.58	gold quality
adrenal gland	UBERON:0002369	74.80	gold quality
calcaneal tendon	UBERON:0003701	73.68	gold quality
left coronary artery	UBERON:0001626	72.67	gold quality
hypothalamus	UBERON:0001898	72.22	gold quality
islet of Langerhans	UBERON:0000006	71.05	gold quality
right adrenal gland cortex	UBERON:0035827	70.79	gold quality
colon	UBERON:0001155	70.54	gold quality
heart	UBERON:0000948	69.53	gold quality
multicellular organism	UBERON:0000468	68.76	gold quality
anterior cingulate cortex	UBERON:0009835	68.43	gold quality
substantia nigra	UBERON:0002038	67.10	gold quality
muscle of leg	UBERON:0001383	66.95	gold quality
saliva-secreting gland	UBERON:0001044	66.78	gold quality
gastrocnemius	UBERON:0001388	65.91	gold quality
left lobe of thyroid gland	UBERON:0001120	65.86	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	65.81	gold quality
tibial nerve	UBERON:0001323	65.42	gold quality
tibial artery	UBERON:0007610	65.28	gold quality
lymph node	UBERON:0000029	65.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snora57	ENSMUSG00000070167
rattus_norvegicus	LOC120100346	ENSRNOG00000054533

Paralogs (3): (ENSG00000212529), (ENSG00000212567), (ENSG00000223027)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.