SNORA59A

Summary

SNORA59A (small nucleolar RNA, H/ACA box 59A, HGNC:32653) is a small nucleolar RNA gene on chromosome 1p36.21.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677885 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32653
Approved symbol	SNORA59A
Name	small nucleolar RNA, H/ACA box 59A
Location	1p36.21
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA59
Ensembl gene	ENSG00000239149
Ensembl biotype	snoRNA
Entrez	677885
RNAcentral	URS0000056589 — snoRNA, 152 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000459326

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000459326 — 1 exons

Exon	Start	End
ENSE00001807584	12507246	12507397

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 93.39.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	93.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.20	gold quality
prefrontal cortex	UBERON:0000451	85.38	gold quality
sural nerve	UBERON:0015488	82.73	gold quality
liver	UBERON:0002107	76.77	gold quality
corpus callosum	UBERON:0002336	76.23	gold quality
blood	UBERON:0000178	75.79	gold quality
skeletal muscle tissue	UBERON:0001134	74.68	gold quality
kidney	UBERON:0002113	74.68	gold quality
calcaneal tendon	UBERON:0003701	74.51	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	73.27	gold quality
adult mammalian kidney	UBERON:0000082	72.40	gold quality
lymph node	UBERON:0000029	71.96	gold quality
placenta	UBERON:0001987	71.94	gold quality
right lobe of thyroid gland	UBERON:0001119	71.35	gold quality
lung	UBERON:0002048	71.22	gold quality
right ovary	UBERON:0002118	70.44	gold quality
skin of leg	UBERON:0001511	70.06	gold quality
fundus of stomach	UBERON:0001160	69.48	gold quality
heart left ventricle	UBERON:0002084	69.33	gold quality
heart	UBERON:0000948	69.10	gold quality
myometrium	UBERON:0001296	69.07	gold quality
tibial artery	UBERON:0007610	69.06	gold quality
mucosa of transverse colon	UBERON:0004991	68.74	gold quality
muscle of leg	UBERON:0001383	68.73	gold quality
islet of Langerhans	UBERON:0000006	68.71	gold quality
left lobe of thyroid gland	UBERON:0001120	68.30	gold quality
monocyte	CL:0000576	68.26	gold quality
esophagus mucosa	UBERON:0002469	68.24	gold quality
bone marrow	UBERON:0002371	68.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (2): (ENSG00000251775), (ENSG00000252870)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.