SNORA59B

Summary

SNORA59B (small nucleolar RNA, H/ACA box 59B, HGNC:32658) is a small nucleolar RNA gene on chromosome 17p11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677882 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32658
Approved symbol	SNORA59B
Name	small nucleolar RNA, H/ACA box 59B
Location	17p11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA59
Ensembl gene	ENSG00000266079
Ensembl biotype	snoRNA
Entrez	677882
RNAcentral	URS0000056589 — snoRNA, 152 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000578183

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578183 — 1 exons

Exon	Start	End
ENSE00002734612	19557211	19557911

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 81.63.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	81.63	gold quality
lower esophagus mucosa	UBERON:0035834	81.53	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.79	gold quality
skin of leg	UBERON:0001511	78.77	gold quality
bone marrow cell	CL:0002092	78.75	gold quality
zone of skin	UBERON:0000014	78.26	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.99	gold quality
uterine cervix	UBERON:0000002	77.73	gold quality
adrenal tissue	UBERON:0018303	77.53	gold quality
skin of abdomen	UBERON:0001416	77.40	gold quality
endocervix	UBERON:0000458	75.63	gold quality
esophagus mucosa	UBERON:0002469	74.76	gold quality
left lobe of thyroid gland	UBERON:0001120	74.65	gold quality
vagina	UBERON:0000996	74.48	gold quality
thyroid gland	UBERON:0002046	74.21	gold quality
right lobe of thyroid gland	UBERON:0001119	74.09	gold quality
tibial artery	UBERON:0007610	74.03	gold quality
popliteal artery	UBERON:0002250	74.02	gold quality
ectocervix	UBERON:0012249	73.66	gold quality
tibial nerve	UBERON:0001323	73.29	gold quality
subcutaneous adipose tissue	UBERON:0002190	73.05	gold quality
prostate gland	UBERON:0002367	71.89	gold quality
heart left ventricle	UBERON:0002084	71.84	gold quality
adipose tissue	UBERON:0001013	71.41	gold quality
skeletal muscle tissue	UBERON:0001134	71.34	gold quality
esophagus	UBERON:0001043	71.19	gold quality
thoracic mammary gland	UBERON:0005200	70.99	gold quality
liver	UBERON:0002107	70.90	gold quality
ascending aorta	UBERON:0001496	70.73	gold quality
tonsil	UBERON:0002372	70.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.71

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.