SNORA5C

Summary

SNORA5C (small nucleolar RNA, H/ACA box 5C, HGNC:32590) is a small nucleolar RNA gene on chromosome 7p13.

Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA5C, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).

Source: NCBI Gene 677796 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32590
Approved symbol	SNORA5C
Name	small nucleolar RNA, H/ACA box 5C
Location	7p13
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA5c
Ensembl gene	ENSG00000201772
Ensembl biotype	snoRNA
OMIM	611335
Entrez	677796
RNAcentral	URS000072157F — snoRNA, 137 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364902

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364902 — 1 exons

Exon	Start	End
ENSE00001439665	45104906	45105042

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 98.08.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.08	gold quality
corpus callosum	UBERON:0002336	97.08	gold quality
calcaneal tendon	UBERON:0003701	96.74	gold quality
adrenal tissue	UBERON:0018303	95.69	gold quality
granulocyte	CL:0000094	93.89	gold quality
right uterine tube	UBERON:0001302	92.03	gold quality
metanephros cortex	UBERON:0010533	90.78	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.25	gold quality
transverse colon	UBERON:0001157	89.75	gold quality
lower esophagus mucosa	UBERON:0035834	89.60	gold quality
right ovary	UBERON:0002118	89.41	gold quality
small intestine Peyer’s patch	UBERON:0003454	89.13	gold quality
spleen	UBERON:0002106	88.58	gold quality
stomach	UBERON:0000945	88.48	gold quality
body of pancreas	UBERON:0001150	88.38	gold quality
body of uterus	UBERON:0009853	88.30	gold quality
small intestine	UBERON:0002108	88.28	gold quality
left ovary	UBERON:0002119	88.22	gold quality
minor salivary gland	UBERON:0001830	87.87	gold quality
blood	UBERON:0000178	87.81	gold quality
body of stomach	UBERON:0001161	87.72	gold quality
ovary	UBERON:0000992	87.70	gold quality
intestine	UBERON:0000160	87.60	gold quality
colon	UBERON:0001155	87.42	gold quality
saliva-secreting gland	UBERON:0001044	87.29	gold quality
right lobe of thyroid gland	UBERON:0001119	87.27	gold quality
prostate gland	UBERON:0002367	87.00	gold quality
fundus of stomach	UBERON:0001160	86.96	gold quality
myometrium	UBERON:0001296	86.84	gold quality
cortex of kidney	UBERON:0001225	86.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.38

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snora5c	ENSMUSG00000065686
rattus_norvegicus	Snora5c	ENSRNOG00000057537

Paralogs (3): SNORA5B (ENSG00000200656), SNORA5A (ENSG00000206838), (ENSG00000207002)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.