SNORA63

Summary

SNORA63 (small nucleolar RNA, H/ACA box 63, HGNC:10106) is a small nucleolar RNA gene on chromosome 3q27.3.

Predicted to be involved in RNA processing. Part of box H/ACA RNP complex.

Source: NCBI Gene 6043 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10106
Approved symbol	SNORA63
Name	small nucleolar RNA, H/ACA box 63
Location	3q27.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	E3, E3-2, SNORA63A
Ensembl gene	ENSG00000200320
Ensembl biotype	snoRNA
OMIM	180647
Entrez	6043
RNAcentral	URS00004B4AC7 — snoRNA, 135 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000363450

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363450 — 1 exons

Exon	Start	End
ENSE00001438213	186787300	186787431

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 99.93.

Top tissues by expression

34 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stomach	UBERON:0000945	99.93	gold quality
intestine	UBERON:0000160	99.92	gold quality
lung	UBERON:0002048	99.92	gold quality
adrenal tissue	UBERON:0018303	99.92	gold quality
adult mammalian kidney	UBERON:0000082	99.91	gold quality
colon	UBERON:0001155	99.89	gold quality
liver	UBERON:0002107	99.76	gold quality
sural nerve	UBERON:0015488	99.60	gold quality
heart	UBERON:0000948	99.16	gold quality
tibial nerve	UBERON:0001323	94.95	gold quality
kidney	UBERON:0002113	94.48	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	93.38	gold quality
frontal cortex	UBERON:0001870	92.46	gold quality
heart left ventricle	UBERON:0002084	91.25	gold quality
blood	UBERON:0000178	90.11	gold quality
right frontal lobe	UBERON:0002810	84.16	gold quality
endometrium	UBERON:0001295	82.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.06	gold quality
left lobe of thyroid gland	UBERON:0001120	80.71	gold quality
tibial artery	UBERON:0007610	79.61	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.14	gold quality
subcutaneous adipose tissue	UBERON:0002190	74.36	gold quality
cerebral cortex	UBERON:0000956	71.44	gold quality
substantia nigra	UBERON:0002038	69.48	gold quality
islet of Langerhans	UBERON:0000006	68.37	gold quality
brain	UBERON:0000955	68.27	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.19	gold quality
nucleus accumbens	UBERON:0001882	66.41	gold quality
anterior cingulate cortex	UBERON:0009835	66.06	gold quality
hypothalamus	UBERON:0001898	58.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm26447	ENSMUSG00000064382
rattus_norvegicus	LOC120095726	ENSRNOG00000056834

Paralogs (10): SNORA63E (ENSG00000199363), SNORA63 (ENSG00000199473), SNORA63 (ENSG00000199552), SNORA63 (ENSG00000199633), SNORA63B (ENSG00000200418), SNORA63D (ENSG00000201229), SNORA63C (ENSG00000201448), SNORA63 (ENSG00000201791), SNORA63 (ENSG00000202449), SNORA63 (ENSG00000252448)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.