SNORA68

Summary

SNORA68 (small nucleolar RNA, H/ACA box 68, HGNC:10225) is a small nucleolar RNA gene on chromosome 19p13.11.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26780 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10225
Approved symbol	SNORA68
Name	small nucleolar RNA, H/ACA box 68
Location	19p13.11
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U68, SNORA68A
Ensembl gene	ENSG00000207166
Ensembl biotype	snoRNA
Entrez	26780
RNAcentral	URS00005357F7 — snoRNA, 133 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384437

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384437 — 1 exons

Exon	Start	End
ENSE00001499445	17862588	17862720

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 99.76.

Top tissues by expression

83 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.76	gold quality
sural nerve	UBERON:0015488	99.69	gold quality
lung	UBERON:0002048	99.51	gold quality
liver	UBERON:0002107	95.58	gold quality
blood	UBERON:0000178	85.94	gold quality
stomach	UBERON:0000945	83.50	gold quality
skeletal muscle tissue	UBERON:0001134	80.86	gold quality
kidney	UBERON:0002113	79.92	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	79.53	gold quality
adult mammalian kidney	UBERON:0000082	75.05	gold quality
calcaneal tendon	UBERON:0003701	74.46	gold quality
intestine	UBERON:0000160	74.42	gold quality
heart	UBERON:0000948	73.02	gold quality
monocyte	CL:0000576	70.76	gold quality
right lobe of liver	UBERON:0001114	68.86	gold quality
colon	UBERON:0001155	68.53	gold quality
saliva-secreting gland	UBERON:0001044	67.37	gold quality
prefrontal cortex	UBERON:0000451	66.82	gold quality
islet of Langerhans	UBERON:0000006	66.35	gold quality
muscle of leg	UBERON:0001383	65.87	gold quality
placenta	UBERON:0001987	65.30	gold quality
minor salivary gland	UBERON:0001830	65.04	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.34	gold quality
spleen	UBERON:0002106	63.09	gold quality
adenohypophysis	UBERON:0002196	63.03	gold quality
tibial nerve	UBERON:0001323	62.97	gold quality
gastrocnemius	UBERON:0001388	62.82	gold quality
heart left ventricle	UBERON:0002084	62.30	gold quality
frontal cortex	UBERON:0001870	61.19	gold quality
hypothalamus	UBERON:0001898	60.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Tumor-educated platelet SNORA58, SNORA68 and SNORD93 as novel diagnostic biomarkers for esophageal cancer. (PMID:37129021)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snora68	ENSMUSG00000077563
rattus_norvegicus	LOC120097581	ENSRNOG00000051532

Paralogs (5): SNORA68B (ENSG00000201388), (ENSG00000201407), (ENSG00000212565), (ENSG00000251715), (ENSG00000252458)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.