SNORA70

Summary

SNORA70 (small nucleolar RNA, H/ACA box 70, HGNC:10231) is a small nucleolar RNA gene on chromosome Xq28.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26778 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10231
Approved symbol	SNORA70
Name	small nucleolar RNA, H/ACA box 70
Location	Xq28
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U70, DXS648E
Ensembl gene	ENSG00000207165
Ensembl biotype	snoRNA
Entrez	26778
RNAcentral	URS00000D55EA — snoRNA, 135 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384436

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384436 — 1 exons

Exon	Start	End
ENSE00001807595	154400281	154400415

Expression profiles

Bgee: expression breadth broad, 26 present calls, max score 99.63.

Top tissues by expression

26 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.63	gold quality
stomach	UBERON:0000945	99.61	gold quality
kidney	UBERON:0002113	99.59	gold quality
colon	UBERON:0001155	99.58	gold quality
adult mammalian kidney	UBERON:0000082	99.54	gold quality
intestine	UBERON:0000160	99.48	gold quality
heart	UBERON:0000948	99.39	gold quality
sural nerve	UBERON:0015488	99.31	gold quality
lung	UBERON:0002048	98.26	gold quality
liver	UBERON:0002107	96.42	gold quality
blood	UBERON:0000178	94.58	gold quality
upper lobe of left lung	UBERON:0008952	88.47	gold quality
skin of leg	UBERON:0001511	87.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.55	gold quality
anterior cingulate cortex	UBERON:0009835	87.20	gold quality
hypothalamus	UBERON:0001898	86.33	gold quality
gastrocnemius	UBERON:0001388	84.66	gold quality
myometrium	UBERON:0001296	80.88	gold quality
calcaneal tendon	UBERON:0003701	77.37	gold quality
right lobe of thyroid gland	UBERON:0001119	76.26	gold quality
left lobe of thyroid gland	UBERON:0001120	75.69	gold quality
caudate nucleus	UBERON:0001873	70.47	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.07	gold quality
nucleus accumbens	UBERON:0001882	64.69	gold quality
islet of Langerhans	UBERON:0000006	60.69	gold quality
left testis	UBERON:0004533	44.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (35): SNORA70 (ENSG00000200237), SNORA70 (ENSG00000201376), SNORA70 (ENSG00000201945), SNORA70 (ENSG00000202379), SNORA70 (ENSG00000202389), SNORA70H (ENSG00000206637), SNORA70G (ENSG00000206650), SNORA70 (ENSG00000206661), SNORA70F (ENSG00000206869), SNORA70 (ENSG00000206886), SNORA70J (ENSG00000206909), SNORA70B (ENSG00000206937), SNORA70 (ENSG00000206958), SNORA70 (ENSG00000207098), SNORA70E (ENSG00000207221), SNORA70 (ENSG00000207244), SNORA70C (ENSG00000207268), SNORA70I (ENSG00000207274), SNORA70 (ENSG00000251796), SNORA70 (ENSG00000251893), SNORA70 (ENSG00000251925), SNORA70 (ENSG00000252014), SNORA70 (ENSG00000252133), SNORA70 (ENSG00000252199), SNORA70 (ENSG00000252258), SNORA70 (ENSG00000252505), SNORA70 (ENSG00000252526), SNORA70 (ENSG00000252657), SNORA70 (ENSG00000252724), SNORA70 (ENSG00000252969), SNORA70 (ENSG00000253027), SNORA70 (ENSG00000253042), SNORA70D (ENSG00000263666), SNORA70 (ENSG00000276094), SNORA70 (ENSG00000278010)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.