SNORA71A

Summary

SNORA71A (small nucleolar RNA, H/ACA box 71A, HGNC:10232) is a small nucleolar RNA gene on chromosome 20q11.23.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26777 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10232
Approved symbol	SNORA71A
Name	small nucleolar RNA, H/ACA box 71A
Location	20q11.23
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U71a
Ensembl gene	ENSG00000225091
Ensembl biotype	snoRNA
Entrez	26777
RNAcentral	URS00002B3FE4 — snoRNA, 138 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364729

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364729 — 1 exons

Exon	Start	End
ENSE00001439492	38427309	38427442

Expression profiles

Bgee: expression breadth broad, 77 present calls, max score 98.86.

Top tissues by expression

77 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	98.86	gold quality
adult mammalian kidney	UBERON:0000082	96.13	gold quality
lung	UBERON:0002048	93.00	gold quality
kidney	UBERON:0002113	89.55	gold quality
liver	UBERON:0002107	88.79	gold quality
blood	UBERON:0000178	88.77	gold quality
stomach	UBERON:0000945	83.69	gold quality
prefrontal cortex	UBERON:0000451	76.27	gold quality
monocyte	CL:0000576	71.75	gold quality
Ammon’s horn	UBERON:0001954	71.73	gold quality
calcaneal tendon	UBERON:0003701	71.41	gold quality
heart	UBERON:0000948	71.01	gold quality
islet of Langerhans	UBERON:0000006	70.13	gold quality
gastrocnemius	UBERON:0001388	69.14	gold quality
right lobe of thyroid gland	UBERON:0001119	69.01	gold quality
bone marrow	UBERON:0002371	67.81	gold quality
intestine	UBERON:0000160	66.84	gold quality
tonsil	UBERON:0002372	66.31	gold quality
sural nerve	UBERON:0015488	66.18	gold quality
multicellular organism	UBERON:0000468	65.81	gold quality
prostate gland	UBERON:0002367	64.56	gold quality
right lobe of liver	UBERON:0001114	63.38	gold quality
metanephros cortex	UBERON:0010533	63.27	gold quality
colon	UBERON:0001155	62.91	gold quality
tibial artery	UBERON:0007610	62.88	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.41	gold quality
upper lobe of left lung	UBERON:0008952	62.33	gold quality
urinary bladder	UBERON:0001255	62.24	gold quality
body of pancreas	UBERON:0001150	61.78	gold quality
ascending aorta	UBERON:0001496	61.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Identification of snoRNA SNORA71A as a Novel Biomarker in Prognosis of Hepatocellular Carcinoma. (PMID:33062075)
• SNORA71A Promotes Colorectal Cancer Cell Proliferation, Migration, and Invasion. (PMID:33083486)
• Small nucleolar RNA SNORA71A promotes epithelial-mesenchymal transition by maintaining ROCK2 mRNA stability in breast cancer. (PMID:35100495)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm26003	ENSMUSG00000064995
mus_musculus	Gm55920	ENSMUSG00002075645
rattus_norvegicus	Snora71a	ENSRNOG00000059422

Paralogs (7): SNORA60 (ENSG00000199266), SNORA71D (ENSG00000200354), SNORA71 (ENSG00000201393), SNORA71C (ENSG00000201512), SNORA71 (ENSG00000201811), SNORA71E (ENSG00000274309), SNORA71 (ENSG00000277034)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.