SNORA73A

Summary

SNORA73A (small nucleolar RNA, H/ACA box 73A, HGNC:10115) is a small nucleolar RNA gene on chromosome 1p36.1.

Predicted to be involved in RNA processing. Located in nucleus. Part of box H/ACA RNP complex.

Source: NCBI Gene 6080 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10115
Approved symbol	SNORA73A
Name	small nucleolar RNA, H/ACA box 73A
Location	1p36.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U17A, E1-7, E1b, E1
Ensembl gene	ENSG00000274266
Ensembl biotype	snoRNA
OMIM	180645
Entrez	6080
RNAcentral	URS00000DE3E2 — snoRNA, 207 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364938

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364938 — 1 exons

Exon	Start	End
ENSE00001439701	28507366	28507571

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 99.92.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 16.0877 / max 621.3061, expressed in 1585 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
1806	14.9758	1559
1807	1.1119	435

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.92	gold quality
colonic epithelium	UBERON:0000397	99.60	gold quality
sural nerve	UBERON:0015488	99.52	gold quality
bone marrow cell	CL:0002092	99.47	gold quality
tonsil	UBERON:0002372	99.35	gold quality
corpus callosum	UBERON:0002336	97.68	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.60	gold quality
urinary bladder	UBERON:0001255	89.68	gold quality
skeletal muscle tissue	UBERON:0001134	89.64	gold quality
cortical plate	UBERON:0005343	85.42	gold quality
liver	UBERON:0002107	85.35	gold quality
cortex of kidney	UBERON:0001225	82.84	gold quality
calcaneal tendon	UBERON:0003701	82.83	gold quality
blood	UBERON:0000178	82.47	gold quality
hindlimb stylopod muscle	UBERON:0004252	79.71	gold quality
lung	UBERON:0002048	79.70	gold quality
prefrontal cortex	UBERON:0000451	79.60	gold quality
uterine cervix	UBERON:0000002	79.50	gold quality
monocyte	CL:0000576	78.99	gold quality
kidney	UBERON:0002113	78.93	gold quality
stomach	UBERON:0000945	73.89	gold quality
primary visual cortex	UBERON:0002436	73.50	gold quality
thoracic mammary gland	UBERON:0005200	72.21	gold quality
superior frontal gyrus	UBERON:0002661	71.65	gold quality
adrenal gland	UBERON:0002369	71.28	gold quality
lymph node	UBERON:0000029	70.81	gold quality
ovary	UBERON:0000992	69.86	gold quality
islet of Langerhans	UBERON:0000006	69.51	gold quality
intestine	UBERON:0000160	69.20	gold quality
myometrium	UBERON:0001296	69.06	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression. (PMID:38240925)

Cross-species orthologs

0 orthologs

Paralogs (7): RNU105C (ENSG00000199212), SNORA73 (ENSG00000199977), SNORA73B (ENSG00000200087), RNU105B (ENSG00000201348), SNORA73 (ENSG00000201816), SNORA73 (ENSG00000222145), SNORA73 (ENSG00000253090)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.