SNORA73B

Summary

SNORA73B (small nucleolar RNA, H/ACA box 73B, HGNC:10116) is a small nucleolar RNA gene on chromosome 1p35.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26768 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10116
Approved symbol	SNORA73B
Name	small nucleolar RNA, H/ACA box 73B
Location	1p35.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U17B, E1c
Ensembl gene	ENSG00000200087
Ensembl biotype	snoRNA
OMIM	603239
Entrez	26768
RNAcentral	URS00006422E6 — snoRNA, 204 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000363217

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363217 — 1 exons

Exon	Start	End
ENSE00001437980	28508559	28508762

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 99.93.

FANTOM5 (CAGE): breadth broad, TPM avg 1.7710 / max 211.6936, expressed in 564 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
1809	1.7710	564

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.93	gold quality
colonic epithelium	UBERON:0000397	99.88	gold quality
sural nerve	UBERON:0015488	99.75	gold quality
bone marrow cell	CL:0002092	99.57	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	99.08	gold quality
corpus callosum	UBERON:0002336	99.02	gold quality
lower esophagus mucosa	UBERON:0035834	95.62	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.32	gold quality
skeletal muscle tissue	UBERON:0001134	93.53	gold quality
tonsil	UBERON:0002372	92.59	gold quality
calcaneal tendon	UBERON:0003701	92.38	gold quality
bone marrow	UBERON:0002371	91.74	gold quality
esophagus mucosa	UBERON:0002469	89.97	gold quality
granulocyte	CL:0000094	89.64	gold quality
right ovary	UBERON:0002118	88.51	gold quality
lung	UBERON:0002048	87.40	gold quality
blood	UBERON:0000178	87.32	gold quality
uterine cervix	UBERON:0000002	87.28	gold quality
vagina	UBERON:0000996	86.57	gold quality
ovary	UBERON:0000992	86.39	gold quality
left ovary	UBERON:0002119	86.32	gold quality
ectocervix	UBERON:0012249	86.27	gold quality
left uterine tube	UBERON:0001303	86.06	gold quality
spleen	UBERON:0002106	85.46	gold quality
right uterine tube	UBERON:0001302	85.20	gold quality
cortex of kidney	UBERON:0001225	85.18	gold quality
liver	UBERON:0002107	85.18	gold quality
upper lobe of left lung	UBERON:0008952	84.97	gold quality
mucosa of transverse colon	UBERON:0004991	84.79	gold quality
leukocyte	CL:0000738	84.36	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.03

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression. (PMID:38240925)

Cross-species orthologs

0 orthologs

Paralogs (7): RNU105C (ENSG00000199212), SNORA73 (ENSG00000199977), RNU105B (ENSG00000201348), SNORA73 (ENSG00000201816), SNORA73 (ENSG00000222145), SNORA73 (ENSG00000253090), SNORA73A (ENSG00000274266)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.