SNORA74A

Summary

SNORA74A (small nucleolar RNA, H/ACA box 74A, HGNC:10119) is a small nucleolar RNA gene on chromosome 5q31.2.

Predicted to be involved in RNA processing. Part of box H/ACA RNP complex.

Source: NCBI Gene 26821 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10119
Approved symbol	SNORA74A
Name	small nucleolar RNA, H/ACA box 74A
Location	5q31.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U19
Ensembl gene	ENSG00000200959
Ensembl biotype	snoRNA
OMIM	621089
Entrez	26821
RNAcentral	URS0000148398 — snoRNA, 200 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364089

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364089 — 1 exons

Exon	Start	End
ENSE00001438852	139278781	139278978

Expression profiles

Bgee: expression breadth ubiquitous, 137 present calls, max score 99.25.

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.25	gold quality
colonic epithelium	UBERON:0000397	99.04	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	98.86	gold quality
bone marrow cell	CL:0002092	96.98	gold quality
sural nerve	UBERON:0015488	96.62	gold quality
tonsil	UBERON:0002372	75.99	gold quality
prefrontal cortex	UBERON:0000451	71.76	gold quality
monocyte	CL:0000576	70.43	gold quality
islet of Langerhans	UBERON:0000006	69.01	gold quality
stomach	UBERON:0000945	68.64	gold quality
uterine cervix	UBERON:0000002	67.53	gold quality
rectum	UBERON:0001052	66.48	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.34	gold quality
adrenal gland	UBERON:0002369	65.26	gold quality
lower esophagus mucosa	UBERON:0035834	64.86	gold quality
muscle of leg	UBERON:0001383	64.71	gold quality
gastrocnemius	UBERON:0001388	64.62	gold quality
vermiform appendix	UBERON:0001154	63.72	gold quality
esophagus mucosa	UBERON:0002469	63.03	gold quality
esophagus	UBERON:0001043	62.91	gold quality
myocardium	UBERON:0002349	62.72	gold quality
right lobe of liver	UBERON:0001114	62.47	gold quality
pancreas	UBERON:0001264	62.44	gold quality
corpus callosum	UBERON:0002336	62.10	gold quality
body of pancreas	UBERON:0001150	62.08	gold quality
metanephros cortex	UBERON:0010533	61.77	gold quality
ectocervix	UBERON:0012249	61.31	gold quality
adult mammalian kidney	UBERON:0000082	61.26	gold quality
thoracic aorta	UBERON:0001515	60.33	gold quality
ascending aorta	UBERON:0001496	60.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snora74a	ENSMUSG00000065649
rattus_norvegicus	Snora74a	ENSRNOG00000051492

Paralogs (8): SNORA74B (ENSG00000212402), SNORA74 (ENSG00000252129), SNORA74D (ENSG00000252213), SNORA74 (ENSG00000252305), SNORA74 (ENSG00000252917), SNORA74C-1 (ENSG00000265733), SNORA74 (ENSG00000272025), SNORA74C-2 (ENSG00000288603)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.