SNORA74C-1

Summary

SNORA74C-1 (small nucleolar RNA, H/ACA box 74C-1, HGNC:52217) is a small nucleolar RNA gene on chromosome 10q11.23.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109616974 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52217
Approved symbol	SNORA74C-1
Name	small nucleolar RNA, H/ACA box 74C-1
Location	10q11.23
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000265733
Ensembl biotype	snoRNA
Entrez	109616974
RNAcentral	URS0000ABD877 — snoRNA, 204 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000580726

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000580726 — 1 exons

Exon	Start	End
ENSE00002717285	45984610	45984810

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 95.32.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.32	gold quality
bone marrow	UBERON:0002371	73.50	gold quality
adrenal tissue	UBERON:0018303	72.39	gold quality
kidney	UBERON:0002113	71.21	gold quality
monocyte	CL:0000576	70.28	gold quality
sural nerve	UBERON:0015488	70.22	gold quality
primary visual cortex	UBERON:0002436	70.12	gold quality
prefrontal cortex	UBERON:0000451	69.51	gold quality
adult mammalian kidney	UBERON:0000082	69.43	gold quality
skeletal muscle tissue	UBERON:0001134	68.26	silver quality
islet of Langerhans	UBERON:0000006	67.47	gold quality
corpus callosum	UBERON:0002336	66.21	gold quality
liver	UBERON:0002107	66.19	gold quality
blood	UBERON:0000178	66.17	gold quality
duodenum	UBERON:0002114	65.83	gold quality
cortex of kidney	UBERON:0001225	65.51	gold quality
lymph node	UBERON:0000029	64.43	gold quality
placenta	UBERON:0001987	63.43	gold quality
muscle of leg	UBERON:0001383	62.94	gold quality
descending thoracic aorta	UBERON:0002345	62.71	gold quality
right adrenal gland	UBERON:0001233	62.42	gold quality
right adrenal gland cortex	UBERON:0035827	62.23	gold quality
gastrocnemius	UBERON:0001388	62.21	gold quality
uterine cervix	UBERON:0000002	62.19	gold quality
vermiform appendix	UBERON:0001154	61.72	gold quality
right lobe of liver	UBERON:0001114	61.63	gold quality
calcaneal tendon	UBERON:0003701	61.03	gold quality
stomach	UBERON:0000945	60.86	gold quality
substantia nigra	UBERON:0002038	60.73	gold quality
Brodmann (1909) area 9	UBERON:0013540	60.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.49

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm23946	ENSMUSG00000077611
rattus_norvegicus	LOC120097670	ENSRNOG00000061440

Paralogs (8): SNORA74A (ENSG00000200959), SNORA74B (ENSG00000212402), SNORA74 (ENSG00000252129), SNORA74D (ENSG00000252213), SNORA74 (ENSG00000252305), SNORA74 (ENSG00000252917), SNORA74 (ENSG00000272025), SNORA74C-2 (ENSG00000288603)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.