SNORA74C-2

Summary

SNORA74C-2 (small nucleolar RNA, H/ACA box 74C-2, HGNC:52218) is a small nucleolar RNA gene on chromosome 10q11.23.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109617009 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52218
Approved symbol	SNORA74C-2
Name	small nucleolar RNA, H/ACA box 74C-2
Location	10q11.23
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000288603
Ensembl biotype	snoRNA
Entrez	109617009
RNAcentral	URS0000BC453E — snoRNA, 204 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000674332

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000674332 — 1 exons

Exon	Start	End
ENSE00003898173	49954214	49954414

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 87.11.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.11	gold quality
skeletal muscle tissue	UBERON:0001134	73.00	gold quality
monocyte	CL:0000576	70.60	gold quality
sural nerve	UBERON:0015488	70.22	gold quality
primary visual cortex	UBERON:0002436	70.12	gold quality
liver	UBERON:0002107	69.58	gold quality
bone marrow	UBERON:0002371	69.47	gold quality
gall bladder	UBERON:0002110	68.22	gold quality
adrenal tissue	UBERON:0018303	67.48	gold quality
prefrontal cortex	UBERON:0000451	67.19	gold quality
adult mammalian kidney	UBERON:0000082	66.59	gold quality
blood	UBERON:0000178	65.98	gold quality
kidney	UBERON:0002113	64.61	gold quality
corpus callosum	UBERON:0002336	64.35	gold quality
islet of Langerhans	UBERON:0000006	64.19	gold quality
stomach	UBERON:0000945	64.03	gold quality
urinary bladder	UBERON:0001255	63.32	gold quality
right lobe of liver	UBERON:0001114	63.12	gold quality
vermiform appendix	UBERON:0001154	62.39	gold quality
cortex of kidney	UBERON:0001225	60.74	gold quality
placenta	UBERON:0001987	60.57	gold quality
muscle of leg	UBERON:0001383	59.75	gold quality
gastrocnemius	UBERON:0001388	58.95	gold quality
lung	UBERON:0002048	58.91	gold quality
adrenal gland	UBERON:0002369	58.79	gold quality
right coronary artery	UBERON:0001625	58.57	gold quality
heart	UBERON:0000948	58.44	gold quality
left adrenal gland cortex	UBERON:0035825	58.10	gold quality
descending thoracic aorta	UBERON:0002345	58.09	gold quality
body of pancreas	UBERON:0001150	57.47	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm23946	ENSMUSG00000077611
rattus_norvegicus	LOC120097670	ENSRNOG00000061440

Paralogs (8): SNORA74A (ENSG00000200959), SNORA74B (ENSG00000212402), SNORA74 (ENSG00000252129), SNORA74D (ENSG00000252213), SNORA74 (ENSG00000252305), SNORA74 (ENSG00000252917), SNORA74C-1 (ENSG00000265733), SNORA74 (ENSG00000272025)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.