SNORA75B

Summary

SNORA75B (small nucleolar RNA, H/ACA box 75B, HGNC:52220) is a small nucleolar RNA gene on chromosome 4p15.32.

Predicted to be involved in RNA processing. Predicted to act upstream of or within response to bacterium. Predicted to be located in nucleolus.

Source: NCBI Gene 109616994 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52220
Approved symbol	SNORA75B
Name	small nucleolar RNA, H/ACA box 75B
Location	4p15.32
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000206780
Ensembl biotype	snoRNA
Entrez	109616994
RNAcentral	URS00006BA8E0 — snoRNA, 137 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384053

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384053 — 1 exons

Exon	Start	End
ENSE00001807234	17320746	17320882

Expression profiles

Bgee: expression breadth broad, 18 present calls, max score 77.64.

Top tissues by expression

18 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	77.64	gold quality
blood	UBERON:0000178	76.61	gold quality
tibial artery	UBERON:0007610	73.86	gold quality
left adrenal gland cortex	UBERON:0035825	73.22	gold quality
liver	UBERON:0002107	71.08	gold quality
lung	UBERON:0002048	70.19	gold quality
cerebellar hemisphere	UBERON:0002245	69.81	gold quality
gastrocnemius	UBERON:0001388	69.15	gold quality
endometrium	UBERON:0001295	65.14	gold quality
subcutaneous adipose tissue	UBERON:0002190	63.33	gold quality
body of uterus	UBERON:0009853	62.55	gold quality
transverse colon	UBERON:0001157	62.31	gold quality
endocervix	UBERON:0000458	61.79	gold quality
putamen	UBERON:0001874	60.92	gold quality
substantia nigra	UBERON:0002038	60.36	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	60.35	gold quality
stomach	UBERON:0000945	51.28	gold quality
left testis	UBERON:0004533	45.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
danio_rerio	SNORA75	ENSDARG00000081440
danio_rerio	SNORA75	ENSDARG00000083582
mus_musculus	Gm25038	ENSMUSG00000064862
mus_musculus	Gm56482	ENSMUSG00002076594
rattus_norvegicus	Snora75	ENSRNOG00000052748

Paralogs (7): SNORA75 (ENSG00000206885), SNORA75 (ENSG00000212432), SNORA75 (ENSG00000212440), SNORA75 (ENSG00000212533), SNORA75 (ENSG00000212580), SNORA75 (ENSG00000212593), SNORA75 (ENSG00000212620)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.