SNORA77B

Summary

SNORA77B (small nucleolar RNA, H/ACA box 77B, HGNC:52221) is a small nucleolar RNA gene on chromosome 22q11.21.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109617010 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52221
Approved symbol	SNORA77B
Name	small nucleolar RNA, H/ACA box 77B
Location	22q11.21
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000264346
Ensembl biotype	snoRNA
Entrez	109617010
RNAcentral	URS00006FB8B0 — snoRNA, 125 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000578179

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578179 — 1 exons

Exon	Start	End
ENSE00002695389	20126402	20126526

Expression profiles

Bgee: expression breadth broad, 81 present calls, max score 98.96.

Top tissues by expression

81 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	98.96	gold quality
sural nerve	UBERON:0015488	98.73	gold quality
liver	UBERON:0002107	87.08	gold quality
lung	UBERON:0002048	85.35	gold quality
duodenum	UBERON:0002114	83.14	gold quality
blood	UBERON:0000178	82.93	gold quality
kidney	UBERON:0002113	80.67	gold quality
myometrium	UBERON:0001296	79.08	gold quality
left uterine tube	UBERON:0001303	75.70	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	75.06	gold quality
stomach	UBERON:0000945	74.87	gold quality
heart	UBERON:0000948	73.54	gold quality
descending thoracic aorta	UBERON:0002345	73.50	gold quality
body of uterus	UBERON:0009853	73.31	gold quality
tibial nerve	UBERON:0001323	72.56	gold quality
endometrium	UBERON:0001295	72.26	gold quality
intestine	UBERON:0000160	72.19	gold quality
islet of Langerhans	UBERON:0000006	71.50	gold quality
monocyte	CL:0000576	71.42	gold quality
adult mammalian kidney	UBERON:0000082	71.12	gold quality
skeletal muscle tissue	UBERON:0001134	70.81	silver quality
multicellular organism	UBERON:0000468	69.44	gold quality
lower esophagus	UBERON:0013473	67.86	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	67.54	gold quality
lower esophagus muscularis layer	UBERON:0035833	67.30	gold quality
small intestine	UBERON:0002108	66.29	gold quality
Brodmann (1909) area 9	UBERON:0013540	65.90	gold quality
lower esophagus mucosa	UBERON:0035834	65.89	gold quality
spleen	UBERON:0002106	65.87	gold quality
muscle of leg	UBERON:0001383	65.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	SNORA77B	ENSDARG00000086007
mus_musculus	Gm25777	ENSMUSG00000080364
rattus_norvegicus	Snora77b	ENSRNOG00000052026

Paralogs (3): (ENSG00000221083), (ENSG00000221498), SNORA77 (ENSG00000221643)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.