SNORA8

Summary

SNORA8 (small nucleolar RNA, H/ACA box 8, HGNC:32596) is a small nucleolar RNA gene on chromosome 11q21.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 654320 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32596
Approved symbol	SNORA8
Name	small nucleolar RNA, H/ACA box 8
Location	11q21
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA8
Ensembl gene	ENSG00000207304
Ensembl biotype	snoRNA
Entrez	654320
RNAcentral	URS00003A960A — snoRNA, 139 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384574

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384574 — 1 exons

Exon	Start	End
ENSE00001807893	93732361	93732499

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 99.74.

FANTOM5 (CAGE): breadth broad, TPM avg 1.9497 / max 325.6449, expressed in 663 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
121831	1.9497	663

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.74	gold quality
adrenal tissue	UBERON:0018303	99.32	gold quality
liver	UBERON:0002107	96.90	gold quality
lung	UBERON:0002048	96.80	gold quality
heart	UBERON:0000948	96.61	gold quality
tibial nerve	UBERON:0001323	95.37	gold quality
stomach	UBERON:0000945	95.17	gold quality
colon	UBERON:0001155	92.09	gold quality
intestine	UBERON:0000160	91.18	gold quality
anterior cingulate cortex	UBERON:0009835	91.08	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	89.20	gold quality
kidney	UBERON:0002113	88.87	gold quality
blood	UBERON:0000178	88.31	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.96	gold quality
heart left ventricle	UBERON:0002084	83.57	gold quality
adult mammalian kidney	UBERON:0000082	82.15	gold quality
gastrocnemius	UBERON:0001388	81.75	gold quality
brain	UBERON:0000955	79.74	gold quality
monocyte	CL:0000576	79.70	gold quality
muscle of leg	UBERON:0001383	76.69	gold quality
skin of leg	UBERON:0001511	76.63	gold quality
myometrium	UBERON:0001296	75.92	gold quality
subcutaneous adipose tissue	UBERON:0002190	75.22	gold quality
skeletal muscle tissue	UBERON:0001134	74.21	gold quality
right frontal lobe	UBERON:0002810	73.61	gold quality
adipose tissue	UBERON:0001013	73.02	gold quality
tibial artery	UBERON:0007610	70.74	gold quality
islet of Langerhans	UBERON:0000006	70.53	gold quality
left lobe of thyroid gland	UBERON:0001120	70.16	gold quality
body of pancreas	UBERON:0001150	67.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm25791	ENSMUSG00000065226
mus_musculus	Gm26236	ENSMUSG00000093277

Paralogs (4): (ENSG00000206977), (ENSG00000207100), (ENSG00000207410), (ENSG00000212586)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.