SNORA91

Summary

SNORA91 (small nucleolar RNA, H/ACA box 91, HGNC:50395) is a gene on chromosome 21q22.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50395
Approved symbol	SNORA91
Name	small nucleolar RNA, H/ACA box 91
Location	21q22.3
Locus type	RNA, small nucleolar
Status	Approved
Entrez	106635524
RNAcentral	URS00008E3A08 — snoRNA, 178 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1002027857 (21:41949612 C>G), RS1002059111 (21:41949926 G>A), RS1006415070 (21:41947973 T>A), RS1006417630 (21:41948767 G>A), RS1007963114 (21:41948869 T>TA,TG), RS1008920434 (21:41949625 C>T), RS1008926479 (21:41948333 T>C), RS1010623592 (21:41948074 T>C), RS1011865370 (21:41948902 T>A), RS1012116540 (21:41948683 C>T), RS1012861092 (21:41948217 A>G), RS1013522583 (21:41949245 G>C), RS1015056371 (21:41948413 T>A), RS1015916152 (21:41947992 C>G), RS1016058911 (21:41949617 T>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Smoke	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.