SNORD104

Summary

SNORD104 (small nucleolar RNA, C/D box 104, HGNC:32768) is a small nucleolar RNA gene on chromosome 17q23.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692227 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32768
Approved symbol	SNORD104
Name	small nucleolar RNA, C/D box 104
Location	17q23.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U104
Ensembl gene	ENSG00000199753
Ensembl biotype	snoRNA
Entrez	692227
RNAcentral	URS00000C304D — snoRNA, 80 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000362883

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000362883 — 1 exons

Exon	Start	End
ENSE00001437646	64146083	64146152

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 99.66.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8207 / max 28.7072, expressed in 390 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
162247	0.8207	390

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.66	gold quality
lower esophagus mucosa	UBERON:0035834	99.34	gold quality
vermiform appendix	UBERON:0001154	99.01	gold quality
right uterine tube	UBERON:0001302	98.95	gold quality
body of pancreas	UBERON:0001150	98.88	gold quality
left ovary	UBERON:0002119	98.83	gold quality
spleen	UBERON:0002106	98.77	gold quality
granulocyte	CL:0000094	98.66	gold quality
right ovary	UBERON:0002118	98.62	gold quality
left adrenal gland cortex	UBERON:0035825	98.53	gold quality
left adrenal gland	UBERON:0001234	98.33	gold quality
ovary	UBERON:0000992	98.29	gold quality
right lung	UBERON:0002167	98.25	gold quality
apex of heart	UBERON:0002098	98.22	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	98.19	gold quality
right lobe of liver	UBERON:0001114	98.17	gold quality
prostate gland	UBERON:0002367	98.15	gold quality
monocyte	CL:0000576	98.14	gold quality
right adrenal gland	UBERON:0001233	98.01	gold quality
adrenal gland	UBERON:0002369	98.01	gold quality
vagina	UBERON:0000996	97.98	gold quality
duodenum	UBERON:0002114	97.94	gold quality
esophagus mucosa	UBERON:0002469	97.92	gold quality
body of stomach	UBERON:0001161	97.89	gold quality
adrenal tissue	UBERON:0018303	97.86	gold quality
mucosa of transverse colon	UBERON:0004991	97.81	gold quality
liver	UBERON:0002107	97.80	gold quality
adenohypophysis	UBERON:0002196	97.68	gold quality
small intestine	UBERON:0002108	97.65	gold quality
left uterine tube	UBERON:0001303	97.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.46

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2’-O-methylation of PARP1. (PMID:36566215)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord104	ENSMUSG00000065126
rattus_norvegicus	Snord104	ENSRNOG00000056422

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.