SNORD107

Summary

SNORD107 (small nucleolar RNA, C/D box 107, HGNC:32771) is a small nucleolar RNA gene on chromosome 15q11.2.

Small nucleolar RNAs (snoRNAs) are small non-coding RNAs involved in RNA processing. Box C/D class snoRNAs are involved in site-specific 2-prime-O-ribose methylation of preribosomal RNA precursors. This snoRNA is located in a cluster of genes including the SNURF-SNRPN gene, which serves as a host for multiple snoRNAs.

Source: NCBI Gene 91380 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
• Dosage sensitivity (ClinGen): haploinsufficiency no evidence, triplosensitivity no evidence

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32771
Approved symbol	SNORD107
Name	small nucleolar RNA, C/D box 107
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-436
Ensembl gene	ENSG00000276314
Ensembl biotype	snoRNA
Entrez	91380
RNAcentral	URS000061A08C — snoRNA, 75 nt, 16 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000459433

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000459433 — 1 exons

Exon	Start	End
ENSE00001808297	24981994	24982068

Expression profiles

Bgee: expression breadth tissue_specific, 8 present calls, max score 98.42.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1470 / max 217.0966, expressed in 319 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
145504	1.1470	319

Top tissues by expression

8 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
Brodmann (1909) area 9	UBERON:0013540	98.42	gold quality
sural nerve	UBERON:0015488	94.98	gold quality
liver	UBERON:0002107	93.06	gold quality
lung	UBERON:0002048	88.71	gold quality
saliva-secreting gland	UBERON:0001044	78.89	gold quality
blood	UBERON:0000178	68.26	gold quality
adrenal tissue	UBERON:0018303	49.87	gold quality
skin of abdomen	UBERON:0001416	44.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Functional genomics

ClinGen dosage: haploinsufficiency 0 (no evidence), triplosensitivity 0 (no evidence). ClinGen Gene Dosage Map

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord107	ENSMUSG00000089375
rattus_norvegicus	Snord107	ENSRNOG00000058701

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.