SNORD108

Summary

SNORD108 (small nucleolar RNA, C/D box 108, HGNC:32772) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 338427 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
• Dosage sensitivity (ClinGen): haploinsufficiency no evidence, triplosensitivity no evidence

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32772
Approved symbol	SNORD108
Name	small nucleolar RNA, C/D box 108
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-437
Ensembl gene	ENSG00000239014
Ensembl biotype	snoRNA
Entrez	338427
RNAcentral	URS000075C7E2 — snoRNA, 69 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000459332

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000459332 — 1 exons

Exon	Start	End
ENSE00001808821	24986925	24986995

Expression profiles

Bgee: expression breadth broad, 21 present calls, max score 95.45.

Top tissues by expression

21 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	95.45	gold quality
islet of Langerhans	UBERON:0000006	74.99	gold quality
body of stomach	UBERON:0001161	73.64	gold quality
heart left ventricle	UBERON:0002084	71.35	gold quality
blood	UBERON:0000178	70.58	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.72	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.98	gold quality
tibial nerve	UBERON:0001323	64.06	gold quality
nucleus accumbens	UBERON:0001882	61.49	gold quality
transverse colon	UBERON:0001157	59.19	gold quality
skin of leg	UBERON:0001511	58.34	gold quality
amygdala	UBERON:0001876	57.57	gold quality
right atrium auricular region	UBERON:0006631	54.03	gold quality
anterior cingulate cortex	UBERON:0009835	52.14	gold quality
prostate gland	UBERON:0002367	51.55	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.52	gold quality
skin of abdomen	UBERON:0001416	50.29	gold quality
cerebellar hemisphere	UBERON:0002245	49.18	silver quality
liver	UBERON:0002107	45.09	silver quality
gastrocnemius	UBERON:0001388	41.83	silver quality
upper lobe of left lung	UBERON:0008952	35.65	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Functional genomics

ClinGen dosage: haploinsufficiency 0 (no evidence), triplosensitivity 0 (no evidence). ClinGen Gene Dosage Map

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.