SNORD109A

Summary

SNORD109A (small nucleolar RNA, C/D box 109A, HGNC:32773) is a small nucleolar RNA gene on chromosome 15q11.2.

This gene encodes a C/D box-type small nucleolar RNA that is expressed predominantly in the brain. Expression of this RNA is not detectable in the brains of patients with Prader-Willi syndrome.

Source: NCBI Gene 338428 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32773
Approved symbol	SNORD109A
Name	small nucleolar RNA, C/D box 109A
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-438a
Ensembl gene	ENSG00000274640
Ensembl biotype	snoRNA
Entrez	338428
RNAcentral	URS000011E0DE — snoRNA, 67 nt, 22 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000459128

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000459128 — 1 exons

Exon	Start	End
ENSE00001807931	25041974	25042040

Expression profiles

Bgee: expression breadth broad, 15 present calls, max score 90.87.

Top tissues by expression

15 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	90.87	gold quality
sural nerve	UBERON:0015488	89.52	gold quality
tibial nerve	UBERON:0001323	77.86	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.41	gold quality
blood	UBERON:0000178	70.56	gold quality
body of stomach	UBERON:0001161	67.94	gold quality
transverse colon	UBERON:0001157	59.57	gold quality
omental fat pad	UBERON:0010414	58.85	gold quality
skin of leg	UBERON:0001511	56.85	gold quality
lower esophagus muscularis layer	UBERON:0035833	53.88	gold quality
hypothalamus	UBERON:0001898	51.12	gold quality
anterior cingulate cortex	UBERON:0009835	50.24	gold quality
tibial artery	UBERON:0007610	50.03	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	49.11	gold quality
muscle layer of sigmoid colon	UBERON:0035805	38.50	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (1): SNORD109B (ENSG00000239169)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.