SNORD111

Summary

SNORD111 (small nucleolar RNA, C/D box 111, HGNC:32776) is a small nucleolar RNA gene on chromosome 16q22.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692214 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32776
Approved symbol	SNORD111
Name	small nucleolar RNA, C/D box 111
Location	16q22.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-82
Ensembl gene	ENSG00000221066
Ensembl biotype	snoRNA
Entrez	692214
RNAcentral	URS00006D333F — snoRNA, 94 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000408139

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000408139 — 1 exons

Exon	Start	End
ENSE00001564774	70538005	70538098

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 96.47.

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	96.47	gold quality
adrenal tissue	UBERON:0018303	85.60	gold quality
kidney	UBERON:0002113	82.75	gold quality
blood	UBERON:0000178	80.15	gold quality
liver	UBERON:0002107	79.05	gold quality
calcaneal tendon	UBERON:0003701	78.71	gold quality
bone marrow	UBERON:0002371	78.52	gold quality
endometrium	UBERON:0001295	76.34	gold quality
monocyte	CL:0000576	76.02	gold quality
muscle of leg	UBERON:0001383	75.76	gold quality
left uterine tube	UBERON:0001303	74.04	gold quality
gastrocnemius	UBERON:0001388	73.84	gold quality
islet of Langerhans	UBERON:0000006	73.81	gold quality
stomach	UBERON:0000945	73.60	gold quality
adrenal gland	UBERON:0002369	72.16	gold quality
tibial artery	UBERON:0007610	71.49	gold quality
heart	UBERON:0000948	71.37	gold quality
lung	UBERON:0002048	71.13	gold quality
right lobe of liver	UBERON:0001114	70.87	gold quality
body of pancreas	UBERON:0001150	70.52	gold quality
adult mammalian kidney	UBERON:0000082	70.06	gold quality
left adrenal gland cortex	UBERON:0035825	69.71	gold quality
granulocyte	CL:0000094	68.66	gold quality
urinary bladder	UBERON:0001255	68.59	gold quality
heart left ventricle	UBERON:0002084	68.57	gold quality
body of stomach	UBERON:0001161	68.49	gold quality
intestine	UBERON:0000160	68.28	gold quality
left adrenal gland	UBERON:0001234	68.26	gold quality
ascending aorta	UBERON:0001496	68.21	gold quality
amygdala	UBERON:0001876	68.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.59

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Plasma SNORD42B and SNORD111 as potential biomarkers for early diagnosis of non-small cell lung cancer. (PMID:36284435)

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000080744
danio_rerio		ENSDARG00000083268
danio_rerio		ENSDARG00000109897
mus_musculus	Snord111	ENSMUSG00000080396
rattus_norvegicus	Snord111	ENSRNOG00000060911

Paralogs (2): SNORD111B (ENSG00000221514), (ENSG00000252230)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.