SNORD111B

Summary

SNORD111B (small nucleolar RNA, C/D box 111B, HGNC:33579) is a small nucleolar RNA gene on chromosome 16q22.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100113402 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33579
Approved symbol	SNORD111B
Name	small nucleolar RNA, C/D box 111B
Location	16q22.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	hsa-mir-3647
Ensembl gene	ENSG00000221514
Ensembl biotype	snoRNA
Entrez	100113402
RNAcentral	URS0000729A81 — snoRNA, 80 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000408587

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000408587 — 1 exons

Exon	Start	End
ENSE00001565222	70529509	70529588

Expression profiles

Bgee: expression breadth broad, 69 present calls, max score 99.31.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0408 / max 35.8803, expressed in 7 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
154881	0.0408	7

Top tissues by expression

69 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.31	gold quality
calcaneal tendon	UBERON:0003701	87.03	gold quality
adrenal tissue	UBERON:0018303	83.96	gold quality
liver	UBERON:0002107	81.35	gold quality
kidney	UBERON:0002113	79.16	gold quality
blood	UBERON:0000178	79.09	gold quality
endometrium	UBERON:0001295	77.34	gold quality
islet of Langerhans	UBERON:0000006	77.17	gold quality
stomach	UBERON:0000945	77.17	gold quality
heart	UBERON:0000948	76.89	gold quality
adrenal gland	UBERON:0002369	75.06	gold quality
putamen	UBERON:0001874	74.20	gold quality
tibial nerve	UBERON:0001323	74.17	gold quality
monocyte	CL:0000576	72.94	gold quality
tonsil	UBERON:0002372	72.07	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.73	gold quality
lung	UBERON:0002048	71.20	gold quality
gastrocnemius	UBERON:0001388	70.51	gold quality
body of stomach	UBERON:0001161	69.83	gold quality
heart left ventricle	UBERON:0002084	68.76	gold quality
intestine	UBERON:0000160	68.23	gold quality
right lobe of liver	UBERON:0001114	67.99	gold quality
granulocyte	CL:0000094	67.76	gold quality
rectum	UBERON:0001052	67.72	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	67.70	gold quality
transverse colon	UBERON:0001157	67.17	gold quality
body of pancreas	UBERON:0001150	67.16	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.71	gold quality
right frontal lobe	UBERON:0002810	66.40	gold quality
right atrium auricular region	UBERON:0006631	65.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• TP53 mediated miR-3647-5p prevents progression of cervical carcinoma by targeting AGR2. (PMID:31436390)

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000080744
danio_rerio		ENSDARG00000083268
danio_rerio		ENSDARG00000109897
mus_musculus	Gm22193	ENSMUSG00000080518
rattus_norvegicus	Snord111b	ENSRNOG00000057770

Paralogs (2): SNORD111 (ENSG00000221066), (ENSG00000252230)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.