SNORD112

Summary

SNORD112 (small nucleolar RNA, C/D box 112, HGNC:32777) is a small nucleolar RNA gene on chromosome 14q32.31.

Small nucleolar RNAs (snoRNAs), like SNORD112, guide the formation of 2-prime O-methylation of ribosomal RNA (rRNA) and U small nuclear RNAs (snRNAs) through a specific RNA duplex at each modification site (Cavaille et al., 2002 [PubMed 12045206]).

Source: NCBI Gene 692215 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32777
Approved symbol	SNORD112
Name	small nucleolar RNA, C/D box 112
Location	14q32.31
Locus type	RNA, small nucleolar
Status	Approved
Aliases	14q(0)
Ensembl gene	ENSG00000275662
Ensembl biotype	snoRNA
OMIM	613649
Entrez	692215
RNAcentral	URS00007014CB — snoRNA, 77 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000458974

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458974 — 1 exons

Exon	Start	End
ENSE00001809180	100897920	100897996

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 98.80.

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.80	gold quality
adrenal tissue	UBERON:0018303	93.86	gold quality
calcaneal tendon	UBERON:0003701	82.08	gold quality
endometrium	UBERON:0001295	79.68	gold quality
lung	UBERON:0002048	75.34	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	74.18	gold quality
islet of Langerhans	UBERON:0000006	73.80	gold quality
liver	UBERON:0002107	73.24	gold quality
stomach	UBERON:0000945	72.37	gold quality
right adrenal gland cortex	UBERON:0035827	71.86	gold quality
adrenal gland	UBERON:0002369	71.77	gold quality
gall bladder	UBERON:0002110	70.84	gold quality
gastrocnemius	UBERON:0001388	70.41	gold quality
hypothalamus	UBERON:0001898	70.11	gold quality
adult mammalian kidney	UBERON:0000082	69.86	gold quality
left adrenal gland cortex	UBERON:0035825	69.84	gold quality
heart	UBERON:0000948	69.82	gold quality
heart left ventricle	UBERON:0002084	69.75	gold quality
Brodmann (1909) area 9	UBERON:0013540	69.71	gold quality
right adrenal gland	UBERON:0001233	69.36	gold quality
blood	UBERON:0000178	69.06	gold quality
left ovary	UBERON:0002119	68.97	gold quality
Ammon’s horn	UBERON:0001954	68.85	gold quality
ovary	UBERON:0000992	68.72	gold quality
left adrenal gland	UBERON:0001234	68.49	gold quality
body of pancreas	UBERON:0001150	68.46	gold quality
substantia nigra	UBERON:0002038	68.40	gold quality
right ovary	UBERON:0002118	68.23	gold quality
tibial nerve	UBERON:0001323	67.76	gold quality
prostate gland	UBERON:0002367	67.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (2): (ENSG00000238966), (ENSG00000252170)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.