SNORD114-21

Summary

SNORD114-21 (small nucleolar RNA, C/D box 114-21, HGNC:33009) is a small nucleolar RNA gene on chromosome 14q32.31.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 767599 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33009
Approved symbol	SNORD114-21
Name	small nucleolar RNA, C/D box 114-21
Location	14q32.31
Locus type	RNA, small nucleolar
Status	Approved
Aliases	14q(II-21)
Ensembl gene	ENSG00000272344
Ensembl biotype	snoRNA
Entrez	767599
RNAcentral	URS00006B8E06 — snoRNA, 72 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000606412

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606412 — 1 exons

Exon	Start	End
ENSE00003699637	100981975	100982046

Expression profiles

Bgee: expression breadth broad, 73 present calls, max score 99.53.

Top tissues by expression

73 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.53	gold quality
sural nerve	UBERON:0015488	93.21	gold quality
lung	UBERON:0002048	90.78	gold quality
calcaneal tendon	UBERON:0003701	90.39	gold quality
stomach	UBERON:0000945	88.34	gold quality
kidney	UBERON:0002113	85.52	gold quality
small intestine	UBERON:0002108	81.13	gold quality
placenta	UBERON:0001987	78.19	gold quality
endometrium	UBERON:0001295	76.94	gold quality
heart	UBERON:0000948	76.24	gold quality
intestine	UBERON:0000160	76.03	gold quality
thoracic mammary gland	UBERON:0005200	75.77	gold quality
gastrocnemius	UBERON:0001388	75.19	gold quality
adult mammalian kidney	UBERON:0000082	74.75	gold quality
liver	UBERON:0002107	74.59	gold quality
substantia nigra	UBERON:0002038	73.80	gold quality
islet of Langerhans	UBERON:0000006	73.38	gold quality
hypothalamus	UBERON:0001898	72.30	gold quality
Ammon’s horn	UBERON:0001954	72.10	gold quality
gall bladder	UBERON:0002110	72.08	gold quality
esophagus mucosa	UBERON:0002469	71.79	gold quality
body of stomach	UBERON:0001161	70.93	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.25	gold quality
amygdala	UBERON:0001876	70.08	gold quality
anterior cingulate cortex	UBERON:0009835	69.73	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.70	gold quality
corpus callosum	UBERON:0002336	69.54	gold quality
body of uterus	UBERON:0009853	68.74	gold quality
left adrenal gland cortex	UBERON:0035825	68.71	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.44

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm25854	ENSMUSG00000064726
mus_musculus	Gm23347	ENSMUSG00000065757
rattus_norvegicus	LOC120093407	ENSRNOG00000063750

Paralogs (44): SNORD114-7 (ENSG00000199390), SNORD114-1 (ENSG00000199575), SNORD114-14 (ENSG00000199593), SNORD114-5 (ENSG00000199798), SNORD114-16 (ENSG00000199914), SNORD114-19 (ENSG00000199942), SNORD114-31 (ENSG00000200089), (ENSG00000200150), SNORD113-6 (ENSG00000200215), SNORD114-10 (ENSG00000200279), SNORD113-8 (ENSG00000200367), SNORD114-23 (ENSG00000200406), SNORD114-26 (ENSG00000200413), SNORD114-28 (ENSG00000200480), SNORD114-11 (ENSG00000200608), SNORD114-25 (ENSG00000200612), SNORD113-7 (ENSG00000200632), SNORD114-27 (ENSG00000200636), SNORD114-2 (ENSG00000200823), SNORD114-4 (ENSG00000200832), (ENSG00000201036), SNORD114-9 (ENSG00000201240), SNORD114-13 (ENSG00000201247), SNORD114-6 (ENSG00000201263), SNORD114-30 (ENSG00000201318), (ENSG00000201500), SNORD114-15 (ENSG00000201557), SNORD114-17 (ENSG00000201569), SNORD113-4 (ENSG00000201672), SNORD114-29 (ENSG00000201689), SNORD113-3 (ENSG00000201700), (ENSG00000201710), SNORD114-3 (ENSG00000201839), SNORD114-24 (ENSG00000201899), SNORD113-9 (ENSG00000201950), SNORD114-20 (ENSG00000202048), SNORD114-18 (ENSG00000202142), SNORD113-1 (ENSG00000202191), SNORD114-12 (ENSG00000202270), SNORD114-22 (ENSG00000202293)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.