SNORD114-3

Summary

SNORD114-3 (small nucleolar RNA, C/D box 114-3, HGNC:32991) is a small nucleolar RNA gene on chromosome 14q32.31.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 767579 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32991
Approved symbol	SNORD114-3
Name	small nucleolar RNA, C/D box 114-3
Location	14q32.31
Locus type	RNA, small nucleolar
Status	Approved
Aliases	14q(II-3)
Ensembl gene	ENSG00000201839
Ensembl biotype	snoRNA
Entrez	767579
RNAcentral	URS00007234FC — snoRNA, 75 nt, 8 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364969

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364969 — 1 exons

Exon	Start	End
ENSE00001807667	100953349	100953423

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 98.72.

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.72	gold quality
adrenal tissue	UBERON:0018303	98.18	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.22	gold quality
liver	UBERON:0002107	88.09	gold quality
lung	UBERON:0002048	85.21	gold quality
kidney	UBERON:0002113	84.82	gold quality
calcaneal tendon	UBERON:0003701	84.12	gold quality
placenta	UBERON:0001987	80.25	gold quality
muscle of leg	UBERON:0001383	77.46	gold quality
stomach	UBERON:0000945	75.73	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.11	gold quality
blood	UBERON:0000178	72.87	gold quality
adult mammalian kidney	UBERON:0000082	72.79	gold quality
anterior cingulate cortex	UBERON:0009835	72.51	gold quality
islet of Langerhans	UBERON:0000006	72.48	gold quality
gastrocnemius	UBERON:0001388	72.22	gold quality
substantia nigra	UBERON:0002038	71.96	gold quality
monocyte	CL:0000576	71.57	gold quality
putamen	UBERON:0001874	71.37	gold quality
hypothalamus	UBERON:0001898	71.35	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.21	gold quality
heart	UBERON:0000948	70.68	gold quality
intestine	UBERON:0000160	70.59	gold quality
cerebral cortex	UBERON:0000956	70.48	gold quality
amygdala	UBERON:0001876	70.27	gold quality
heart left ventricle	UBERON:0002084	70.24	gold quality
endometrium	UBERON:0001295	69.92	gold quality
brain	UBERON:0000955	69.79	gold quality
nucleus accumbens	UBERON:0001882	69.76	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.39

Regulation

Is transcription factor: no

Cross-species orthologs

19 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm23736	ENSMUSG00000064487
mus_musculus	Gm22981	ENSMUSG00000064545
mus_musculus	Gm25856	ENSMUSG00000064720
mus_musculus	AF357341	ENSMUSG00000065022
mus_musculus	AF357428	ENSMUSG00000065749
rattus_norvegicus	LOC120093391	ENSRNOG00000053854
rattus_norvegicus	Snord113l1	ENSRNOG00000054892
rattus_norvegicus		ENSRNOG00000076964
rattus_norvegicus		ENSRNOG00000077429
rattus_norvegicus		ENSRNOG00000078431
rattus_norvegicus		ENSRNOG00000081440
rattus_norvegicus		ENSRNOG00000085472
rattus_norvegicus		ENSRNOG00000085838
rattus_norvegicus		ENSRNOG00000086053
rattus_norvegicus		ENSRNOG00000086949
rattus_norvegicus		ENSRNOG00000088877
rattus_norvegicus		ENSRNOG00000089964
rattus_norvegicus		ENSRNOG00000090487
rattus_norvegicus		ENSRNOG00000091221

Paralogs (44): SNORD114-7 (ENSG00000199390), SNORD114-1 (ENSG00000199575), SNORD114-14 (ENSG00000199593), SNORD114-5 (ENSG00000199798), SNORD114-16 (ENSG00000199914), SNORD114-19 (ENSG00000199942), SNORD114-31 (ENSG00000200089), (ENSG00000200150), SNORD113-6 (ENSG00000200215), SNORD114-10 (ENSG00000200279), SNORD113-8 (ENSG00000200367), SNORD114-23 (ENSG00000200406), SNORD114-26 (ENSG00000200413), SNORD114-28 (ENSG00000200480), SNORD114-11 (ENSG00000200608), SNORD114-25 (ENSG00000200612), SNORD113-7 (ENSG00000200632), SNORD114-27 (ENSG00000200636), SNORD114-2 (ENSG00000200823), SNORD114-4 (ENSG00000200832), (ENSG00000201036), SNORD114-9 (ENSG00000201240), SNORD114-13 (ENSG00000201247), SNORD114-6 (ENSG00000201263), SNORD114-30 (ENSG00000201318), (ENSG00000201500), SNORD114-15 (ENSG00000201557), SNORD114-17 (ENSG00000201569), SNORD113-4 (ENSG00000201672), SNORD114-29 (ENSG00000201689), SNORD113-3 (ENSG00000201700), (ENSG00000201710), SNORD114-24 (ENSG00000201899), SNORD113-9 (ENSG00000201950), SNORD114-20 (ENSG00000202048), SNORD114-18 (ENSG00000202142), SNORD113-1 (ENSG00000202191), SNORD114-12 (ENSG00000202270), SNORD114-22 (ENSG00000202293), SNORD113-2 (ENSG00000212384)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.