SNORD114-8

Summary

SNORD114-8 (small nucleolar RNA, C/D box 114-8, HGNC:32996) is a gene on chromosome 14q32.31.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 767584 — RefSeq curated summary.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32996
Approved symbol	SNORD114-8
Name	small nucleolar RNA, C/D box 114-8
Location	14q32.31
Locus type	RNA, small nucleolar
Status	Approved
Aliases	14q(II-8)
Entrez	767584

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1001554702 (14:100963518 G>A), RS1002602568 (14:100964121 A>G), RS1002743309 (14:100963943 G>A,T), RS1002958711 (14:100964371 G>A,T), RS1005943986 (14:100963634 A>G), RS1007616137 (14:100964900 A>T), RS1007630008 (14:100963416 T>C), RS1008090698 (14:100962936 A>C), RS1011063262 (14:100962785 T>C), RS1012540500 (14:100963823 C>T), RS1014761471 (14:100963423 T>C), RS1015058969 (14:100963648 C>T), RS1016088400 (14:100964418 T>C,G), RS1016846758 (14:100964573 T>A,C), RS1017773143 (14:100962987 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

2 total (human), top 2 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	increases expression	1
Benzo(a)pyrene	increases methylation	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.