SNORD115-2

Summary

SNORD115-2 (small nucleolar RNA, C/D box 115-2, HGNC:33021) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033437 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33021
Approved symbol	SNORD115-2
Name	small nucleolar RNA, C/D box 115-2
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-52-2
Ensembl gene	ENSG00000199712
Ensembl biotype	snoRNA
Entrez	100033437
RNAcentral	URS0000211ABF — snoRNA, 82 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000362842

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000362842 — 1 exons

Exon	Start	End
ENSE00001807000	25172635	25172716

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 81.06.

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
Brodmann (1909) area 9	UBERON:0013540	81.06	gold quality
gastrocnemius	UBERON:0001388	74.30	gold quality
body of stomach	UBERON:0001161	73.91	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	73.13	gold quality
heart left ventricle	UBERON:0002084	72.73	gold quality
liver	UBERON:0002107	72.07	gold quality
putamen	UBERON:0001874	68.81	gold quality
prefrontal cortex	UBERON:0000451	68.47	gold quality
substantia nigra	UBERON:0002038	68.23	gold quality
Ammon’s horn	UBERON:0001954	68.22	gold quality
anterior cingulate cortex	UBERON:0009835	68.07	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	67.56	gold quality
esophagus mucosa	UBERON:0002469	66.41	gold quality
skin of leg	UBERON:0001511	66.20	gold quality
brain	UBERON:0000955	66.09	gold quality
hypothalamus	UBERON:0001898	66.01	gold quality
amygdala	UBERON:0001876	65.94	gold quality
right lobe of liver	UBERON:0001114	65.88	gold quality
tibial artery	UBERON:0007610	65.45	gold quality
blood	UBERON:0000178	65.44	gold quality
nucleus accumbens	UBERON:0001882	65.40	gold quality
right frontal lobe	UBERON:0002810	65.31	gold quality
frontal cortex	UBERON:0001870	65.03	gold quality
corpus callosum	UBERON:0002336	64.82	gold quality
thoracic aorta	UBERON:0001515	63.85	gold quality
vagina	UBERON:0000996	63.30	gold quality
spleen	UBERON:0002106	63.30	gold quality
prostate gland	UBERON:0002367	62.97	gold quality
cerebellar hemisphere	UBERON:0002245	62.87	gold quality
transverse colon	UBERON:0001157	62.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-4 (ENSG00000200680), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-22 (ENSG00000201326), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.