SNORD115-21

Summary

SNORD115-21 (small nucleolar RNA, C/D box 115-21, HGNC:33040) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033603 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33040
Approved symbol	SNORD115-21
Name	small nucleolar RNA, C/D box 115-21
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-52-21
Ensembl gene	ENSG00000199833
Ensembl biotype	snoRNA
Entrez	100033603
RNAcentral	URS00000F4646 — snoRNA, 81 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000362963

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000362963 — 1 exons

Exon	Start	End
ENSE00001807282	25208083	25208163

Expression profiles

Bgee: expression breadth broad, 32 present calls, max score 93.85.

Top tissues by expression

32 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	93.85	gold quality
Brodmann (1909) area 9	UBERON:0013540	79.55	gold quality
lung	UBERON:0002048	77.47	gold quality
blood	UBERON:0000178	74.48	gold quality
body of stomach	UBERON:0001161	73.34	gold quality
islet of Langerhans	UBERON:0000006	73.32	gold quality
body of pancreas	UBERON:0001150	72.12	gold quality
ascending aorta	UBERON:0001496	69.61	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.59	gold quality
transverse colon	UBERON:0001157	68.64	gold quality
minor salivary gland	UBERON:0001830	66.95	gold quality
muscle layer of sigmoid colon	UBERON:0035805	65.62	gold quality
Ammon’s horn	UBERON:0001954	65.49	gold quality
thyroid gland	UBERON:0002046	65.10	gold quality
putamen	UBERON:0001874	64.98	gold quality
caudate nucleus	UBERON:0001873	64.12	gold quality
left lobe of thyroid gland	UBERON:0001120	63.39	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	62.27	gold quality
right frontal lobe	UBERON:0002810	61.69	gold quality
anterior cingulate cortex	UBERON:0009835	60.79	gold quality
nucleus accumbens	UBERON:0001882	59.97	gold quality
subcutaneous adipose tissue	UBERON:0002190	59.16	gold quality
cerebellar hemisphere	UBERON:0002245	58.71	gold quality
skin of leg	UBERON:0001511	58.70	gold quality
left ovary	UBERON:0002119	58.40	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.68	gold quality
amygdala	UBERON:0001876	57.07	gold quality
prostate gland	UBERON:0002367	56.94	gold quality
pituitary gland	UBERON:0000007	56.39	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	55.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-4 (ENSG00000200680), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-22 (ENSG00000201326), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.